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'https://openalex.org/W3031872621', 'https://openalex.org/W3031534618', 'https://openalex.org/W3031505833', 'https://openalex.org/W3031449654', 'https://openalex.org/W3031441417', 'https://openalex.org/W3031346570', 'https://openalex.org/W3030972956', 'https://openalex.org/W3030868230', 'https://openalex.org/W3030692868', 'https://openalex.org/W3030442061', 'https://openalex.org/W3030168805', 'https://openalex.org/W3029779073', 'https://openalex.org/W3029645180', 'https://openalex.org/W3029118630', 'https://openalex.org/W3029095879', 'https://openalex.org/W3029033512'], 'abstract_inverted_index': {'目的': [0], '探讨基质金属蛋白酶(MMP)': [1], '2、9及其特异性组织抑制剂(TIMP)在自发性胎膜早破发病中的作用.方法采用RT-PCR方法对8例自发性胎膜早破患者(胎膜早破组)、8例正常阴道分娩产妇(阴道分娩组)以及8例择期剖宫产产妇(剖宫产组)的胎膜组织中MMP-2、MMP-9和TIMP-2、TIMP-1': [2], 'mRNA的表达进行检测.结果': [3], '(1)MMP-2:胎膜早破组为0.849±0.037,阴道分娩组为0.327±0.023,剖宫产组为0.307±0.028.': [4], '胎膜早破组MMP-2表达水平明显高于阴道分娩组和剖宫产组,两组比较,差异有统计学意义(P': [5], '0.05).(2)MMP-9:胎膜早破组为0.026±0.004,阴道分娩组为0.008±0.001,剖宫产组无表达.胎膜早破组MMP-9表达水平明显高于阴道分娩组,两者比较,差异有统计学意义(P': [6], '0.05).结论': [7], 'MMP-2': [8], '、MMP-9及TIMP-2、TIMP-1在胎膜早破患者的胎膜组织中表达失衡,导致胎膜细胞间基质的降解,胎膜细胞间连接强度减弱,最终发生胎膜破裂。': [9]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3030112887', 'counts_by_year': [], 'updated_date': '2024-12-10T15:46:35.137891', 'created_date': '2020-06-05'}