Publication Information

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False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3032694421', 'https://openalex.org/W3031958728', 'https://openalex.org/W3031719981', 'https://openalex.org/W3031534618', 'https://openalex.org/W3031505833', 'https://openalex.org/W3031449654', 'https://openalex.org/W3031441417', 'https://openalex.org/W3030986593', 'https://openalex.org/W3030972956', 'https://openalex.org/W3030868230', 'https://openalex.org/W3030692868', 'https://openalex.org/W3030442061', 'https://openalex.org/W3030168805', 'https://openalex.org/W3030112887', 'https://openalex.org/W3029779073', 'https://openalex.org/W3029645180', 'https://openalex.org/W3029387481', 'https://openalex.org/W3029095879', 'https://openalex.org/W3029033512', 'https://openalex.org/W2291515029'], 'abstract_inverted_index': {'目的:探讨基质金属蛋白酶-2(MMP-2)和组织基质金属蛋白抑制剂-2(TIMP-2)在人甲状腺乳头状癌组织中的表达及其与浸润程度、淋巴结转移的关系.方法:应用免疫组织化学S-P法对56例甲状腺乳头状癌组织及其癌旁正常甲状腺组织中MMP-2和TIMP-2表达情况进行检测.结果:MMP-2和TIMP-2在甲状腺乳头状癌组织中表达的阳性率分别为76.8%(43/56)和37.5%(21/56).在癌旁正常甲状腺组织中表达的阳性率分别为33.9%(19/56)和32.1%(18/56),表明MMP-2在甲状腺乳头状癌中有较高表达率.同时MMP-2和TIMP-2的表达与浸润程度、淋巴结转移有显著相关性(P＜0.05),与肿瘤大小无相关性.结论:MMP-2和TIMP-2的表达与甲状腺乳头状癌浸润程度、淋巴结转移密切相关,可作为判断甲状腺乳头状癌生物学行为和预后的参考指标.': [0]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3032675685', 'counts_by_year': [], 'updated_date': '2024-12-13T09:02:27.791957', 'created_date': '2020-06-05'}