Expression and significance of matrix metalloproteinase 2 and its tissue inhibitor in human endometrial carcinoma

Name: Work Video:
Duration: 3 min 30 s
生秀杰; 阎进; 宋和存; 王沂峰
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'https://openalex.org/W3029033512', 'https://openalex.org/W2976592231', 'https://openalex.org/W2291515029'], 'abstract_inverted_index': {'目的': [0], '探讨基质金属蛋白酶2(MMP-2)与其组织抑制因子2(TIMP-2)在子宫内膜癌中的表达及意义.方法应用免疫组织化学方法对40例子宫内膜癌,12例子宫内膜不典型增生,12例正常子宫内膜中的MMP-2,TIMP-2的表达进行检测,并分析MMP-2,TIMP-2的表达与子宫内膜癌临床病理特征之间的关系.结果': [1], 'MMP-2和TIMP-2在正常子宫内膜、子宫内膜不典型增生及子宫内膜癌的阳性表达率逐渐升高;在子宫内膜癌组织中,MMP-2/TIMP-2阳性表达面积比值随着病理分化程度的降低、肌层浸润的加深及临床分期的升高而逐渐增高.结论': [2], 'MMP-2与TIMP-2的表达与子宫内膜癌的发生相关,MMP-2/TIMP-2表达的不平衡可能是子宫内膜癌发生发展的因素之一。': [3]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3032694421', 'counts_by_year': [], 'updated_date': '2024-12-14T04:57:30.248069', 'created_date': '2020-06-05'}
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