Publication Information

{'id': 'https://openalex.org/W3030831808', 'doi': 'https://doi.org/10.3760/cma.j.issn.1001-9030.2018.02.048', 'title': 'Expression of microRNA-220 in human glioma tissues and its effects on the human glioma cell line U87', 'display_name': 'Expression of microRNA-220 in human glioma tissues and its effects on the human glioma cell line U87', 'publication_year': 2018, 'publication_date': '2018-02-08', 'ids': {'openalex': 'https://openalex.org/W3030831808', 'doi': 'https://doi.org/10.3760/cma.j.issn.1001-9030.2018.02.048', 'mag': '3030831808'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'http://rs.yiigle.com/CN421213201802/1027944.htm', 'pdf_url': None, 'source': None, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': [], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5100345660', 'display_name': 'Yu Li', 'orcid': 'https://orcid.org/0000-0001-8578-7268'}, 'institutions': [], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yu Li', 'raw_affiliation_strings': ['Department of Neurosurgery, Henan People’s Hospital, Zhengzhou 450003, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurosurgery, Henan People’s Hospital, Zhengzhou 450003, China', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5029768249', 'display_name': 'Yong Li', 'orcid': 'https://orcid.org/0000-0002-8910-9787'}, 'institutions': [], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Yong Li', 'raw_affiliation_strings': ['Department of Neurosurgery, Xinzheng People’s Hospital, Xinzheng 451100, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurosurgery, Xinzheng People’s Hospital, Xinzheng 451100, China', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5035848960', 'display_name': 'Jian‐Guo Zhang', 'orcid': 'https://orcid.org/0000-0001-6020-6148'}, 'institutions': [], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Jianguo Zhang', 'raw_affiliation_strings': ['Department of Neurosurgery, Henan People’s Hospital, Zhengzhou 450003, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurosurgery, Henan People’s Hospital, Zhengzhou 450003, China', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 0, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 62}, 'biblio': {'volume': '35', 'issue': '2', 'first_page': '347', 'last_page': '349'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10062', 'display_name': 'MicroRNA in disease regulation', 'score': 0.986, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10062', 'display_name': 'MicroRNA in disease regulation', 'score': 0.986, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11765', 'display_name': 'Circular RNAs in diseases', 'score': 0.9838, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/u87', 'display_name': 'U87', 'score': 0.7434542}], 'concepts': [{'id': 'https://openalex.org/C2778227246', 'wikidata': 'https://www.wikidata.org/wiki/Q1365309', 'display_name': 'Glioma', 'level': 2, 'score': 0.89930594}, {'id': 'https://openalex.org/C128473837', 'wikidata': 'https://www.wikidata.org/wiki/Q7863603', 'display_name': 'U87', 'level': 3, 'score': 0.7434542}, {'id': 'https://openalex.org/C553184892', 'wikidata': 'https://www.wikidata.org/wiki/Q1141429', 'display_name': 'Flow cytometry', 'level': 2, 'score': 0.6977322}, {'id': 'https://openalex.org/C190283241', 'wikidata': 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[], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3032763079', 'https://openalex.org/W3032683727', 'https://openalex.org/W3031869021', 'https://openalex.org/W3031631838', 'https://openalex.org/W3031579642', 'https://openalex.org/W3031546493', 'https://openalex.org/W3031350774', 'https://openalex.org/W3031126564', 'https://openalex.org/W3030539979', 'https://openalex.org/W3030500488', 'https://openalex.org/W3030391453', 'https://openalex.org/W3029950332', 'https://openalex.org/W3029845100', 'https://openalex.org/W3029613523', 'https://openalex.org/W3029315219', 'https://openalex.org/W3028996331', 'https://openalex.org/W2997026551', 'https://openalex.org/W2357121991', 'https://openalex.org/W2073535909', 'https://openalex.org/W205543755'], 'abstract_inverted_index': {'Objective\r\nTo': [0], 'investigate': [1], 'the': [2, 21, 53, 67, 71, 144, 149, 165, 179, 186, 200, 201, 212, 225, 253, 298, 308], 'expression': [3, 88, 130, 293], 'of': [4, 20, 29, 38, 69, 77, 90, 120, 132, 157, 207, 248, 294, 302, 310], 'microRNA': [5], '(miRNA,': [6], 'miR)-220': [7], 'in': [8, 92, 134, 143, 169, 190, 216, 224, 233, 241, 257, 265, 273, 281, 289], 'human': [9, 22, 57], 'glioma': [10, 23, 33, 58, 93, 135, 290, 303, 311], 'tissues': [11, 28, 41, 136, 147], 'and': [12, 18, 84, 94, 231, 271, 300, 305], 'its': [13], 'effects': [14], 'on': [15], 'proliferation,': [16], 'invasion': [17, 110, 214, 301], 'apoptosis': [19, 118, 255, 309], 'cell': [24, 59, 109, 158, 166, 187, 213, 254], 'line': [25, 60], 'U87.\r\n\r\n\r\nMethods\r\nThe': [26], 'tumor': [27], '102': [30], 'patents': [31], 'with': [32, 44, 148, 178, 199], 'were': [34, 50, 63, 73, 97, 112, 137, 221, 238], 'selected.': [35], 'Forty-three': [36], 'cases': [37], 'normal': [39, 81], 'brain': [40, 146], 'from': [42], 'patients': [43], 'traumatic': [45], 'injury': [46], 'undergoing': [47], 'intracranial': [48], 'decompression': [49], 'selected': [51], 'as': [52, 176, 197], 'control': [54, 82, 95], 'group.': [55], 'The': [56, 87, 108, 117, 155, 205, 246], 'U87': [61], 'cells': [62, 72], 'cultured.': [64], 'According': [65], 'to': [66], 'differences': [68], 'transfections,': [70], 'divided': [74], 'into': [75], 'groups': [76, 96, 123], 'miR-220': [78, 80, 85, 91, 133, 170, 180, 191, 202, 217, 226, 234, 242, 258, 266, 274, 282, 295], 'inhibitors,': [79], '(NC)': [83], 'mimics.': [86], 'levels': [89, 131], 'detected': [98], 'by': [99, 114, 126], 'real-time': [100], 'quantitative': [101], 'reverse': [102], 'transcription': [103], 'polymerase': [104], 'chain': [105], 'reaction': [106], '(RT-PCR).': [107], 'abilities': [111, 215], 'tested': [113], 'Transwell': [115, 208], 'assay.': [116], 'rate': [119, 256], 'different': [121], 'transfected': [122], 'was': [124, 174, 195, 262, 278, 286], 'measured': [125], 'flow': [127, 249], 'cytometry.\r\n\r\n\r\nResults\r\nThe': [128], 'relative': [129], '2.45±0.22,': [138], 'significantly': [139], 'higher': [140, 279], 'than': [141, 223, 240, 264, 280], '1.31±0.17': [142], 'healthy': [145], 'difference': [150], 'being': [151], 'statistically': [152], 'significant': [153], '(P=0.008).': [154], 'results': [156, 206, 247], 'counting': [159], 'kit-8': [160], '(CCK-8)': [161], 'assay': [162, 209], 'showed': [163], 'that': [164, 211, 252, 272], 'proliferation': [167, 188, 299], 'speed': [168, 189], 'mimics': [171, 218, 259], 'group': [172, 182, 193, 219, 228, 236, 244, 260, 268, 276, 284], '(2.62±0.26)': [173], 'increased': [175], 'compared': [177, 198], 'NC': [181, 203, 227, 243, 267, 283], '(2.06±0.17,': [183], 'P=0.037),': [184], 'meanwhile': [185], 'inhibitors': [192, 235, 275], '(1.63±0.24)': [194], 'reduced': [196], '(P=0.006).': [204], 'revealed': [210], '(163.8±16.5)': [220], 'stronger': [222], '(131.5±14.3,': [229], 'P=0.008),': [230], 'those': [232], '(108.3±9.9)': [237], 'weaker': [239], '(P=0.041).': [245], 'cytometry': [250], 'demonstrated': [251], '[(10.24±1.73)%]': [261], 'lower': [263], '[(13.92±1.89)%]': [269], '(P=0.039),': [270], '[(20.08±3.29)%]': [277], '(P=0.007).\r\n\r\n\r\nConclusion\r\nMiR-220': [285], 'highly': [287], 'expressed': [288], 'tissues.': [291], 'Down-regulation': [292], 'could': [296, 306], 'inhibit': [297], 'cells,': [304], 'accelerate': [307], 'cells.\r\n\r\n\r\nKey': [312], 'words:': [313], '\r\nGlioma;\xa0MicroRNA-220;\xa0Proliferation;\xa0Invasion;\xa0Apoptosis': [314]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3030831808', 'counts_by_year': [], 'updated_date': '2024-12-14T13:49:23.033812', 'created_date': '2020-06-05'}