Publication Information

{'id': 'https://openalex.org/W3031631838', 'doi': 'https://doi.org/10.3760/cma.j.issn.1671-8925.2017.09.006', 'title': 'Inhibiting effect of microRNA-101 over-expression on human U251 glioma cells', 'display_name': 'Inhibiting effect of microRNA-101 over-expression on human U251 glioma cells', 'publication_year': 2017, 'publication_date': '2017-09-15', 'ids': {'openalex': 'https://openalex.org/W3031631838', 'doi': 'https://doi.org/10.3760/cma.j.issn.1671-8925.2017.09.006', 'mag': '3031631838'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.3760/cma.j.issn.1671-8925.2017.09.006', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764375915', 'display_name': 'Chinese Journal of Neuromedicine', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4320800525', 'host_organization_name': 'Chinese Medical Association', 'host_organization_lineage': 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'https://openalex.org/W3029226705', 'https://openalex.org/W3028807183', 'https://openalex.org/W2468615007', 'https://openalex.org/W2401470254', 'https://openalex.org/W2248626906', 'https://openalex.org/W2114402182', 'https://openalex.org/W2073535909'], 'abstract_inverted_index': {'Objective\r\nTo': [0], 'observe': [1], 'the': [2, 56, 104, 112, 133, 145], 'effect': [3], 'of': [4, 13, 116, 155, 173, 211, 224, 232, 240, 264], 'microRNA-101': [5], '(miR-101)': [6], 'over-expression': [7], 'on': [8], 'proliferation,': [9, 248], 'apoptosis': [10, 108, 201, 225], 'and': [11, 29, 38, 62, 93, 109, 111, 118, 137, 167, 177, 191, 206, 229, 252, 255], 'cycle': [12, 237, 251, 270], 'human': [14, 19], 'glioma': [15, 20, 244], 'cell': [16, 21, 84, 107, 200, 236, 250], 'line': [17, 22], 'U251.\r\n\r\n\r\nMethods\r\nThe': [18], 'U251': [23, 243], 'was': [24, 81, 100, 148, 168], 'routinely': [25], 'cultured': [26], 'in': [27, 55, 106, 132, 144, 242], 'vitro,': [28], 'randomly': [30], 'divided': [31], 'into': [32, 49], 'miR-101': [33, 45, 63, 141, 146, 158, 195, 241, 256], 'group,': [34, 140], 'negative': [35, 59, 134, 178, 192], 'control': [36, 40, 60, 135, 139, 175, 179, 190, 193], 'group': [37, 61, 136, 147, 159, 176, 180, 196], 'blank': [39, 138, 174, 189], 'group.': [41, 64], 'Negative': [42], 'controls': [43], 'or': [44], 'mimics': [46], 'were': [47, 68, 120], 'transfected': [48], 'U25l': [50], 'cells': [51, 57, 156, 219, 245], 'by': [52, 70, 83, 122], 'lipofectamine': [53], 'RNAiMAX': [54], 'from': [58, 157], 'MiR-101': [65], 'expression': [66, 114, 142, 228, 231], 'levels': [67, 115], 'detected': [69, 121], 'real-time': [71], 'fluorescence': [72], 'quantificative': [73], 'PCR': [74], '48': [75, 125, 181], 'h': [76, 95, 126, 164, 182], 'after': [77, 96, 127, 165, 183], 'transfection.': [78, 97], 'Cell': [79], 'viability': [80], 'determined': [82], 'counting': [85], 'kit-8': [86], '(CCK-8)': [87], '12,': [88], '24,': [89], '36,': [90], '48,': [91], '60': [92], '72': [94], 'Flow': [98], 'cytometry': [99], 'used': [101], 'to': [102, 161], 'monitor': [103], 'changes': [105], 'cycle,': [110], 'protein': [113, 226, 234], 'BCL-2': [117, 227], 'P21': [119, 238], 'Western': [123], 'blotting': [124], 'transfection.\r\n\r\n\r\nResults\r\nAs': [128], 'compared': [129, 187], 'with': [130, 188], 'that': [131, 172], 'level': [143], 'significantly': [149, 169, 198, 208, 221], 'up-regulated': [150], '(P<0.05).': [151, 185], 'The': [152], 'survival': [153], 'rate': [154, 202], 'began': [160], 'decrease': [162], '12': [163], 'transfection,': [166], 'lower': [170], 'than': [171], 'transfection': [184], 'As': [186], 'groups,': [194], 'had': [197], 'increased': [199, 230], '([13.73±2.60]%': [203], 'vs.': [204], '[4.40±0.57]%': [205], '[4.23±0.44]%),': [207], 'higher': [209], 'percentage': [210], 'G0/G1': [212], 'stage': [213, 217], 'cells,': [214], 'statistically': [215], 'decreased': [216, 222], 'S': [218], 'percentage,': [220], 'inhibitor': [223], 'key': [233], 'regulating': [235], '(P<005).\r\n\r\n\r\nConclusion\r\nOver-expression': [239], 'can': [246], 'suppress': [247], 'block': [249], 'induce': [253], 'apoptosis,': [254], 'may': [257], 'serve': [258], 'as': [259], 'a': [260], 'new': [261], 'potential': [262], 'target': [263], 'treatment': [265], 'for': [266], 'glioma.\r\n\r\n\r\nKey': [267], 'words:': [268], '\r\nGlioma;\xa0MicroRNA-101;\xa0Apoptosis;\xa0Cell': [269]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3031631838', 'counts_by_year': [], 'updated_date': '2024-12-07T16:24:52.920998', 'created_date': '2020-06-05'}