Publication Information

{'id': 'https://openalex.org/W3030500488', 'doi': 'https://doi.org/10.3760/cma.j.issn.1001-9030.2015.03.029', 'title': 'Effect of microRNA-874 on proliferation and apoptosis in U87 glioma cells', 'display_name': 'Effect of microRNA-874 on proliferation and apoptosis in U87 glioma cells', 'publication_year': 2015, 'publication_date': '2015-03-08', 'ids': {'openalex': 'https://openalex.org/W3030500488', 'doi': 'https://doi.org/10.3760/cma.j.issn.1001-9030.2015.03.029', 'mag': '3030500488'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'http://rs.yiigle.com/CN421213201503/631929.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764660617', 'display_name': 'Zhonghua shiyan waike zazhi', 'issn_l': '1001-9030', 'issn': ['1001-9030'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4320800525', 'host_organization_name': 'Chinese Medical Association', 'host_organization_lineage': 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'https://openalex.org/W3031579642', 'https://openalex.org/W3031546493', 'https://openalex.org/W3031350774', 'https://openalex.org/W3031126564', 'https://openalex.org/W3030912405', 'https://openalex.org/W3030831808', 'https://openalex.org/W3030539979', 'https://openalex.org/W3030391453', 'https://openalex.org/W3029950332', 'https://openalex.org/W3029845100', 'https://openalex.org/W3029735080', 'https://openalex.org/W3029613523', 'https://openalex.org/W3028996331', 'https://openalex.org/W2358358191', 'https://openalex.org/W2357121991', 'https://openalex.org/W2114402182'], 'abstract_inverted_index': {'Objective\r\nTo': [0], 'observe': [1], 'the': [2, 76, 134, 176], 'effects': [3], 'of': [4, 16, 24, 43, 97, 104, 130, 136, 150, 158, 180], 'microRNA(miR)-': [5], '874': [6, 18, 45, 54, 81, 99, 106, 132, 152, 160, 169], 'on': [7], 'proliferation': [8, 64], 'and': [9, 26, 62, 79, 165, 178], 'apoptosis': [10, 144], 'in': [11, 21, 85, 108, 155], 'U87': [12, 59, 109], 'glioma': [13, 60], 'cells.\r\n\r\n\r\nMethods\r\nThe': [14], 'expression': [15, 42, 96, 149], 'miR-': [17, 53, 98, 105, 131, 151, 159, 168], 'was': [19, 46, 56, 65, 72, 82, 153], 'detected': [20], '12': [22], 'cases': [23], 'gliomas': [25], '6': [27], 'nontumor': [28], 'control': [29, 92, 113], 'brain': [30, 93], 'tissues': [31], 'by': [32, 48, 67], 'using': [33], 'real-': [34], 'time': [35], 'fluorescent': [36], 'quantitative': [37], 'polymerase': [38], 'chain': [39], 'reaction(FQPCR).': [40], 'The': [41, 95, 167], 'miRNA-': [44], 'tested': [47], 'FQ-': [49], 'PCR': [50], 'after': [51, 102], 'synthesized': [52], 'mimics': [55, 107], 'transfected': [57], 'into': [58], 'cells': [61, 110, 120, 143], 'cell': [63, 77], 'detect': [66, 75], 'methyl': [68], 'thiazol': [69], 'tetrazolium(MTT).Flow': [70], 'cytometry': [71], 'applied': [73], 'to': [74, 112], 'cycle': [78], 'apoptosis.\r\n\r\n\r\nResults\r\nMiR-': [80], 'down-': [83], 'regulated': [84], 'glioblastoma': [86], 'samples': [87], 'compared': [88, 111], 'with': [89, 163], 'non-': [90], 'tumor': [91], 'tissues.': [94], 'increased': [100], 'significantly': [101], 'transfection': [103], 'group(638.00±80.63': [114], 'vs.': [115], '0.17±0.04,P<': [116], '0.05),': [117], 'meanwhile': [118], 'suppressed': [119], 'proliferation(48': [121], 'h:0.357±0.026': [122], 'vs.0.589±0.021,': [123], 'P<0.05;72': [124], 'h:0.522±0.034': [125], 'vs.0.834±0.035,': [126], 'P<': [127, 147], '0.05).Up-': [128], 'regulation': [129], 'raised': [133], 'percentage': [135], 'G0/G1': [137], 'phase': [138], 'cells[(56.28±1.62)%': [139], 'vs.(48.57±0.88)%,': [140], 'P<0.05]and': [141], 'induced': [142], '[(12.50±0.66)%': [145], 'vs.(4.91±0.15)%,': [146], '0.05].\r\n\r\n\r\nConclusion\r\nThe': [148], 'low': [154], 'glioblastoma.': [156], 'Loss': [157], 'is': [161], 'correlated': [162], 'Tumorigenesis': [164], 'development.': [166], 'might': [170], 'be': [171], 'a': [172], 'valid': [173], 'target': [174], 'for': [175], 'diagnosis': [177], 'treatment': [179], 'glioblastoma.\r\n\r\n\r\nKey': [181], 'words:': [182], '\r\nMicroRNA-874;\xa0Glioblastoma;\xa0Proliferation;\xa0Apoptosis': [183]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3030500488', 'counts_by_year': [], 'updated_date': '2024-12-15T21:05:06.193278', 'created_date': '2020-06-05'}