Publication Information

{'id': 'https://openalex.org/W3030539979', 'doi': 'https://doi.org/10.3760/cma.j.issn.1001-9030.2018.10.033', 'title': 'Researches of microRNA-200a on malignant biological behavior of human glioma cells', 'display_name': 'Researches of microRNA-200a on malignant biological behavior of human glioma cells', 'publication_year': 2018, 'publication_date': '2018-10-08', 'ids': {'openalex': 'https://openalex.org/W3030539979', 'doi': 'https://doi.org/10.3760/cma.j.issn.1001-9030.2018.10.033', 'mag': '3030539979'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'http://rs.yiigle.com/CN421213201810/1071334.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764660617', 'display_name': 'Zhonghua shiyan waike zazhi', 'issn_l': '1001-9030', 'issn': ['1001-9030'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4320800525', 'host_organization_name': 'Chinese Medical Association', 'host_organization_lineage': ['https://openalex.org/P4320800525'], 'host_organization_lineage_names': ['Chinese Medical Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': [], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5080265590', 'display_name': 'Xiao-dong Nie', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210125748', 'display_name': 'First Hospital of Shanxi Medical University', 'ror': 'https://ror.org/02vzqaq35', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210125748']}, {'id': 'https://openalex.org/I17721919', 'display_name': 'Shanxi Medical University', 'ror': 'https://ror.org/0265d1010', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I17721919']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xiaodong Nie', 'raw_affiliation_strings': ['Department of Neurosurgery, the First Affiliated Hospital, Shanxi Medical University, Taiyuan 030001, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurosurgery, the First Affiliated Hospital, Shanxi Medical University, Taiyuan 030001, China', 'institution_ids': ['https://openalex.org/I4210125748', 'https://openalex.org/I17721919']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5063481505', 'display_name': 'Jinhu Li', 'orcid': 'https://orcid.org/0000-0002-6896-9518'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Jinhu Li', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5100374791', 'display_name': 'Xiaodong Liu', 'orcid': 'https://orcid.org/0000-0002-6879-990X'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Xiaodong Liu', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 62}, 'biblio': {'volume': '35', 'issue': '10', 'first_page': '1889', 'last_page': '1891'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11765', 'display_name': 'Circular RNAs in diseases', 'score': 0.9611, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11765', 'display_name': 'Circular RNAs in diseases', 'score': 0.9611, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10062', 'display_name': 'MicroRNA in disease regulation', 'score': 0.9563, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/cell-counting', 'display_name': 'Cell counting', 'score': 0.56569123}], 'concepts': [{'id': 'https://openalex.org/C29537977', 'wikidata': 'https://www.wikidata.org/wiki/Q188941', 'display_name': 'Cell cycle', 'level': 3, 'score': 0.7841646}, {'id': 'https://openalex.org/C190283241', 'wikidata': 'https://www.wikidata.org/wiki/Q14599311', 'display_name': 'Apoptosis', 'level': 2, 'score': 0.7053256}, {'id': 'https://openalex.org/C54009773', 'wikidata': 'https://www.wikidata.org/wiki/Q1429031', 'display_name': 'Transfection', 'level': 3, 'score': 0.7028974}, {'id': 'https://openalex.org/C553184892', 'wikidata': 'https://www.wikidata.org/wiki/Q1141429', 'display_name': 'Flow cytometry', 'level': 2, 'score': 0.66873175}, {'id': 'https://openalex.org/C85265743', 'wikidata': 'https://www.wikidata.org/wiki/Q885458', 'display_name': 'Blot', 'level': 3, 'score': 0.61500835}, {'id': 'https://openalex.org/C62112901', 'wikidata': 'https://www.wikidata.org/wiki/Q189159', 'display_name': 'Cell growth', 'level': 2, 'score': 0.576365}, {'id': 'https://openalex.org/C2583947', 'wikidata': 'https://www.wikidata.org/wiki/Q5058179', 'display_name': 'Cell counting', 'level': 4, 'score': 0.56569123}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.55471313}, {'id': 'https://openalex.org/C199835354', 'wikidata': 'https://www.wikidata.org/wiki/Q15311861', 'display_name': 'Cyclin D1', 'level': 4, 'score': 0.51393574}, {'id': 'https://openalex.org/C81885089', 'wikidata': 'https://www.wikidata.org/wiki/Q189082', 'display_name': 'Cell culture', 'level': 2, 'score': 0.48681614}, {'id': 'https://openalex.org/C2778227246', 'wikidata': 'https://www.wikidata.org/wiki/Q1365309', 'display_name': 'Glioma', 'level': 2, 'score': 0.46549806}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.4527474}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.45150506}, {'id': 'https://openalex.org/C145059251', 'wikidata': 'https://www.wikidata.org/wiki/Q310899', 'display_name': 'microRNA', 'level': 3, 'score': 0.41792834}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.37616202}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.26206926}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.06452015}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.049495637}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'http://rs.yiigle.com/CN421213201810/1071334.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764660617', 'display_name': 'Zhonghua shiyan waike zazhi', 'issn_l': '1001-9030', 'issn': ['1001-9030'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4320800525', 'host_organization_name': 'Chinese Medical Association', 'host_organization_lineage': ['https://openalex.org/P4320800525'], 'host_organization_lineage_names': ['Chinese Medical Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3032752645', 'https://openalex.org/W3032683727', 'https://openalex.org/W3031869021', 'https://openalex.org/W3031631838', 'https://openalex.org/W3031579642', 'https://openalex.org/W3031546493', 'https://openalex.org/W3031256895', 'https://openalex.org/W3031126564', 'https://openalex.org/W3031021646', 'https://openalex.org/W3030831808', 'https://openalex.org/W3030500488', 'https://openalex.org/W3029950332', 'https://openalex.org/W3029845100', 'https://openalex.org/W3029735080', 'https://openalex.org/W3029613523', 'https://openalex.org/W3029226705', 'https://openalex.org/W3029120793', 'https://openalex.org/W3028807183', 'https://openalex.org/W2114402182', 'https://openalex.org/W2073535909'], 'abstract_inverted_index': {'Objective\r\nTo': [0], 'investigate': [1], 'the': [2, 75, 118, 123, 137, 164, 177, 189, 209, 216, 252], 'effect': [3], 'of': [4, 15, 53, 74, 106, 126, 144, 156, 166, 179, 192, 200, 211, 218, 226, 254], 'microRNA': [5], '(miRNA,': [6], 'miR)-200a': [7], 'on': [8], 'proliferation,': [9], 'apoptosis,': [10, 232], 'migration': [11, 88, 154, 241], 'and': [12, 20, 27, 96, 108, 120, 188, 215, 238], 'cell': [13, 17, 37, 71, 81, 87, 97, 153, 231, 235], 'cycle': [14, 98, 236], 'glioma': [16, 36, 230], 'line': [18, 38], 'U251': [19, 39], 'its': [21, 234, 240], 'possible': [22], 'mechanism.\r\n\r\n\r\nMethods\r\nmiR-200a': [23], 'mimics': [24], '(miR-200a': [25], 'group)': [26, 31, 49], 'nonsense': [28], 'sequences': [29], '(Mock': [30], 'were': [32, 99, 147, 221], 'transfected': [33], 'into': [34], 'human': [35], 'in': [40, 128, 136, 170], 'vitro': [41], 'by': [42, 57, 80, 92, 101, 114], 'liposome': [43], 'transient': [44], 'transfection.': [45], 'Blank': [46, 121], 'group': [47, 139, 158, 172, 194, 202], '(Blank': [48], 'group).': [50], 'The': [51, 70, 86, 104, 142, 152], 'expression': [52, 105, 125, 210, 217], 'miR-200a': [54, 127, 129, 145, 157, 171, 193, 201, 227], 'was': [55, 78, 90, 112, 131, 159, 173, 183, 195], 'detected': [56, 79, 91, 100, 113], 'real-time': [58], 'quantitative': [59], 'reverse': [60], 'transcriptase-polymerase': [61], 'chain': [62], 'reaction': [63], '(RT-qPCR)': [64], 'after': [65], 'transfection': [66], 'for': [67, 251], '48': [68], 'hours.': [69], 'proliferation': [72], 'ability': [73, 89, 155], 'three': [76], 'groups': [77], 'counting': [82], 'kit-8': [83], '(CCK-8)': [84], 'method.': [85], 'scratches.': [93], 'Cell': [94], 'apoptosis': [95, 190], 'flow': [102], 'cytometry': [103], 'ZEB1': [107, 212], 'Cyclin': [109, 219], 'D1': [110, 220], 'protein': [111], 'Western': [115, 205], 'blotting.\r\n\r\n\r\nResults\r\nCompared': [116], 'with': [117], 'Mock': [119], 'groups,': [122], 'relative': [124], 'cells': [130, 143, 146, 169, 182], 'significantly': [132, 148, 160, 184, 196, 222], 'higher': [133], 'than': [134, 198], 'that': [135, 199, 208], 'untreated': [138], '(P=0.000,': [140], '0.000).': [141], 'different': [149], '(P=0.028,': [150], '0.010).': [151], 'decreased': [161, 185], '(P=0.031,': [162], '0.030),': [163], 'proportion': [165, 178], 'G0/G1': [167], 'phase': [168, 181], 'increased': [174], '(P=0.011,': [175], '0.013),': [176], 'S': [180], '(P=0.024,': [186], '0.008),': [187], 'rate': [191], 'lower': [197], '(P=0.001,': [203], '0.001).': [204], 'blotting': [206], 'showed': [207], '(P=0.042,': [213], '0.034)': [214], 'down-regulated': [223], '(P=0.020,': [224], '0.013).\r\n\r\n\r\nConclusion\r\nUpregulation': [225], 'can': [228], 'promote': [229], 'block': [233], 'progression': [237], 'inhibit': [239], 'ability,': [242], 'which': [243], 'is': [244], 'expected': [245], 'to': [246], 'be': [247], 'a': [248], 'new': [249], 'target': [250], 'treatment': [253], 'glioma.\r\n\r\n\r\nKey': [255], 'words:': [256], '\r\nGlioma;\xa0MicroRNA-200a;\xa0Apoptosis;\xa0Cell': [257], 'Cycle;\xa0Cell': [258], 'Migration': [259]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3030539979', 'counts_by_year': [], 'updated_date': '2024-12-15T21:05:06.778238', 'created_date': '2020-06-05'}