Publication Information

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'https://openalex.org/W3029845100', 'https://openalex.org/W3029735080', 'https://openalex.org/W3029613523', 'https://openalex.org/W3028807183', 'https://openalex.org/W3024753914', 'https://openalex.org/W2357121991', 'https://openalex.org/W2114402182', 'https://openalex.org/W2073535909'], 'abstract_inverted_index': {'Objective\r\nTo': [0], 'investigate': [1], 'the': [2, 36, 39, 79, 90, 134, 139, 154], 'effect': [3], 'of': [4, 13, 52, 68, 93, 111, 152, 168, 174, 199], 'knocking': [5], 'down': [6], 'miR': [7], '-19a': [8], 'on': [9], 'proliferation': [10, 60, 109], 'and': [11, 43, 58, 71, 83, 160, 183], 'apoptosis': [12, 70, 185], 'human': [14, 187], 'glioma': [15, 188], 'cell': [16, 59, 69, 119, 172, 178, 189], 'line': [17, 190], 'U251': [18, 30], 'in': [19, 122, 186], 'vitro.\r\n\r\n\r\nMethods\r\nU251': [20], 'cells': [21, 31, 157, 163], 'were': [22, 47, 73, 158, 164], 'cultured': [23], 'routinely.': [24], 'MiR-19a': [25], 'inhibitor': [26, 113, 124], 'was': [27, 54, 61, 95, 115, 129, 141], 'transfected': [28], 'into': [29], 'by': [32, 56, 63, 75], 'Lipofectamine': [33], '2000.': [34], 'At': [35], 'same': [37], 'time,': [38], 'negative': [40, 80], 'control': [41, 45, 81, 85, 136], 'group': [42, 46, 82, 114, 125], 'blank': [44, 84, 135], 'established.': [48], 'The': [49, 66, 118, 166], 'expression': [50, 91], 'level': [51, 92], 'miR-19a': [53, 94, 112, 123, 169, 175, 192], 'detected': [55], 'RT-PCR.': [57], 'analyzed': [62], 'CCK-8': [64, 106], 'assay.': [65], 'changes': [67], 'cycle': [72], 'monitored': [74], 'flow': [76], 'cytometry.\r\n\r\n\r\nResults\r\nCompared': [77], 'with': [78, 133], 'group,': [86], 'qRT-PCR': [87], 'showed': [88], 'that': [89, 108], 'significantly': [96, 116], 'reduced': [97], 'after': [98, 126], 'transfection': [99], '(F': [100], '=': [101, 145], '124.72,': [102], 'P': [103, 147], '<': [104, 148], '0.01).': [105, 149], 'revealed': [107], 'ability': [110], 'suppressed.': [117], 'survival': [120], 'rate': [121], '48': [127], 'h': [128], '(48.27±8.23)': [130], '%,': [131], 'compared': [132], 'group(100.00': [137], '%),': [138], 'difference': [140], 'statistically': [142], 'significant': [143], '(t': [144], '12.45,': [146], 'After': [150], 'low-expression': [151, 167], 'miR-19a,': [153], 'G0/G1': [155], 'phase': [156, 162], 'increased': [159], 'S': [161], 'decreased.': [165], 'could': [170], 'induce': [171, 184], 'apoptosis.\r\n\r\n\r\nConclusions\r\nLow-expression': [173], 'can': [176], 'inhibit': [177], 'proliferation,': [179], 'block': [180], 'G1/S': [181], 'transition': [182], 'U251.': [191], 'may': [193], 'serve': [194], 'as': [195], 'an': [196], 'attractive': [197], 'target': [198], 'gene': [200], 'therapy': [201], 'for': [202], 'glioblastoma.\r\n\r\n\r\nKey': [203], 'words:': [204], '\r\nmiR-19a;\xa0Human': [205], 'glioma;\xa0Cell': [206], 'proliferation;\xa0Apoptosis': [207]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3031546493', 'counts_by_year': [], 'updated_date': '2024-12-10T10:07:57.014950', 'created_date': '2020-06-05'}