Title: Antiviral Effect of Chinese Herbal Medicine Xuan-fei-he-jie Formula on Influenza Virus Infection in Mice
Abstract:Objective: To study the effect of Chinese herbal medicine Xuan-fei-he-jie Formula on the treatment of influenza virus infection in mice.Methods: Pulmonary inflammation model was established in mice by...Objective: To study the effect of Chinese herbal medicine Xuan-fei-he-jie Formula on the treatment of influenza virus infection in mice.Methods: Pulmonary inflammation model was established in mice by nasal drop of influenza virus.The effect of prophylaxis and treatment with Xuan-fei-he-jie Formula was investigated in the mice with influenza virus infection.Ribavirin served as control.Results: In the Xuan-fei-he-jie Formula group,the survival rate of infected mice was significantly increased than that in the model group(P0.05),with a prolonged survival time(P0.05).Both the lung index and viral titers were decreased in the Xuan-fei-he-jie Formula group than those in the model group(P0.05).The mouse body weight was significant different in the 2 groups(P0.05).Conclusion: Xuan-fei-he-jie Formula can effectively inhibit the proliferation of influenza virus,decrease lung index,promote survival rate in mice infected by influenza virus.Read More
Publication Year: 2011
Publication Date: 2011-01-01
Language: en
Type: article
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