Title: The Immune Protection of Maxingshigan Decoction on Mice Which Were Infected by A-type Influenza Virus
Abstract:Objective:By observing Maxingshigan Decoction(MXSGD) on immune organ weight index of mice which were infected by A-type influenza virus and levels of IL-2、TNF-β,to explore immune protection of mice wh...Objective:By observing Maxingshigan Decoction(MXSGD) on immune organ weight index of mice which were infected by A-type influenza virus and levels of IL-2、TNF-β,to explore immune protection of mice which were infected by A-type influenza virus. Methods: Use nasal inoculation to establish mouse pulmonary infection model animals by A-type influenza virus. Set up MXSGD group,ribavirin group,Anti-virus particle group,model control group and normal control group. After gavaging drug or normal saline,detection of weight in mice,lung index,spleen index,thymus index,the level of TNF-β,IL-2 in lung tissue. Result: MXSGD can obviously improve mice which were infected by A-type influenza virus:inhibited the rate of weight loss,spleen weight index,thymus index and the level of IL-2 in lung tissue by Immunohistochemical method,and reduce lung weight index and the level of TNF-β in lung tissue. Conclusion: MXSGD by enhancing mice's immune function,regulating a variety of inflammation-associated factor secretion levels to protect mice which were infected by A-type influenza virus.Read More
Publication Year: 2010
Publication Date: 2010-01-01
Language: en
Type: article
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