Publication Information

{'id': 'https://openalex.org/W2105499941', 'doi': 'https://doi.org/10.1248/bpb.34.1352', 'title': 'Oral Administration of Bifidobacterium longum Ameliorates Influenza Virus Infection in Mice', 'display_name': 'Oral Administration of Bifidobacterium longum Ameliorates Influenza Virus Infection in Mice', 'publication_year': 2011, 'publication_date': '2011-01-01', 'ids': {'openalex': 'https://openalex.org/W2105499941', 'doi': 'https://doi.org/10.1248/bpb.34.1352', 'mag': '2105499941', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/21804232'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1248/bpb.34.1352', 'pdf_url': 'https://www.jstage.jst.go.jp/article/bpb/34/8/34_8_1352/_pdf', 'source': {'id': 'https://openalex.org/S165235614', 'display_name': 'Biological and Pharmaceutical Bulletin', 'issn_l': '0918-6158', 'issn': ['0918-6158', '1347-5215'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310313382', 'host_organization_name': 'Pharmaceutical Society of Japan', 'host_organization_lineage': ['https://openalex.org/P4310313382'], 'host_organization_lineage_names': ['Pharmaceutical Society of Japan'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://www.jstage.jst.go.jp/article/bpb/34/8/34_8_1352/_pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5074580847', 'display_name': 'Noriyuki Iwabuchi', 'orcid': 'https://orcid.org/0009-0009-1673-7414'}, 'institutions': [{'id': 'https://openalex.org/I4210166507', 'display_name': 'Food Research and Development Institute', 'ror': 'https://ror.org/05we0sj60', 'country_code': 'BG', 'type': 'education', 'lineage': ['https://openalex.org/I4210166507']}], 'countries': ['BG'], 'is_corresponding': False, 'raw_author_name': 'Noriyuki Iwabuchi', 'raw_affiliation_strings': ['Food Science and Technology Institute, Morinaga Milk Industry Co., Ltd.'], 'affiliations': [{'raw_affiliation_string': 'Food Science and Technology Institute, Morinaga Milk Industry Co., Ltd.', 'institution_ids': ['https://openalex.org/I4210166507']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5051080925', 'display_name': 'Jin‐zhong Xiao', 'orcid': 'https://orcid.org/0000-0002-8512-9086'}, 'institutions': [{'id': 'https://openalex.org/I4210166507', 'display_name': 'Food Research and Development Institute', 'ror': 'https://ror.org/05we0sj60', 'country_code': 'BG', 'type': 'education', 'lineage': ['https://openalex.org/I4210166507']}], 'countries': ['BG'], 'is_corresponding': False, 'raw_author_name': 'Jin-Zhong Xiao', 'raw_affiliation_strings': ['Food Science and Technology Institute, Morinaga Milk Industry Co., Ltd.'], 'affiliations': [{'raw_affiliation_string': 'Food Science and Technology Institute, Morinaga Milk Industry Co., Ltd.', 'institution_ids': ['https://openalex.org/I4210166507']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5043118846', 'display_name': 'Tomoko Yaeshima', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210166507', 'display_name': 'Food Research and Development Institute', 'ror': 'https://ror.org/05we0sj60', 'country_code': 'BG', 'type': 'education', 'lineage': ['https://openalex.org/I4210166507']}], 'countries': ['BG'], 'is_corresponding': False, 'raw_author_name': 'Tomoko Yaeshima', 'raw_affiliation_strings': ['Food Science and Technology Institute, Morinaga Milk Industry Co., Ltd.'], 'affiliations': [{'raw_affiliation_string': 'Food Science and Technology Institute, Morinaga Milk Industry Co., Ltd.', 'institution_ids': ['https://openalex.org/I4210166507']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5049420784', 'display_name': 'Keiji Iwatsuki', 'orcid': 'https://orcid.org/0000-0003-4666-3179'}, 'institutions': [{'id': 'https://openalex.org/I4210166507', 'display_name': 'Food Research and Development Institute', 'ror': 'https://ror.org/05we0sj60', 'country_code': 'BG', 'type': 'education', 'lineage': ['https://openalex.org/I4210166507']}], 'countries': ['BG'], 'is_corresponding': False, 'raw_author_name': 'Keiji Iwatsuki', 'raw_affiliation_strings': ['Food Science and Technology Institute, Morinaga Milk Industry Co., Ltd.'], 'affiliations': [{'raw_affiliation_string': 'Food Science and Technology Institute, Morinaga Milk Industry Co., Ltd.', 'institution_ids': ['https://openalex.org/I4210166507']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.392, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 65, 'citation_normalized_percentile': {'value': 0.849396, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '34', 'issue': '8', 'first_page': '1352', 'last_page': '1355'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10371', 'display_name': 'Immune Response and Inflammation', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10371', 'display_name': 'Immune Response and Inflammation', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10167', 'display_name': 'Influenza Virus Research Studies', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11020', 'display_name': 'Immune Cell Function and Interaction', 'score': 0.9989, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/bifidobacterium-longum', 'display_name': 'Bifidobacterium longum', 'score': 0.7472357}], 'concepts': [{'id': 'https://openalex.org/C2776996202', 'wikidata': 'https://www.wikidata.org/wiki/Q4904768', 'display_name': 'Bifidobacterium longum', 'level': 5, 'score': 0.7472357}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.65335023}, {'id': 'https://openalex.org/C2522874641', 'wikidata': 'https://www.wikidata.org/wiki/Q808', 'display_name': 'Virus', 'level': 2, 'score': 0.6304823}, {'id': 'https://openalex.org/C2777056448', 'wikidata': 'https://www.wikidata.org/wiki/Q285166', 'display_name': 'Oral administration', 'level': 2, 'score': 0.5967524}, {'id': 'https://openalex.org/C2777397205', 'wikidata': 'https://www.wikidata.org/wiki/Q275792', 'display_name': 'Saline', 'level': 2, 'score': 0.5321167}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.44443008}, {'id': 'https://openalex.org/C2776178377', 'wikidata': 'https://www.wikidata.org/wiki/Q188269', 'display_name': 'Interferon', 'level': 2, 'score': 0.41568458}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.36496234}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.3377778}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.3052789}, {'id': 'https://openalex.org/C2780305828', 'wikidata': 'https://www.wikidata.org/wiki/Q132656', 'display_name': 'Bifidobacterium', 'level': 4, 'score': 0.2854533}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.23411942}, {'id': 'https://openalex.org/C100544194', 'wikidata': 'https://www.wikidata.org/wiki/Q41760', 'display_name': 'Fermentation', 'level': 2, 'score': 0.09763923}, {'id': 'https://openalex.org/C31903555', 'wikidata': 'https://www.wikidata.org/wiki/Q1637030', 'display_name': 'Food science', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C2780206646', 'wikidata': 'https://www.wikidata.org/wiki/Q1061596', 'display_name': 'Lactobacillus', 'level': 3, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000893', 'descriptor_name': 'Anti-Inflammatory Agents', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D001644', 'descriptor_name': 'Bifidobacterium', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D008168', 'descriptor_name': 'Lung', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D009975', 'descriptor_name': 'Orthomyxoviridae', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D009976', 'descriptor_name': 'Orthomyxoviridae Infections', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D019936', 'descriptor_name': 'Probiotics', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D015431', 'descriptor_name': 'Weight Loss', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D000284', 'descriptor_name': 'Administration, Oral', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000893', 'descriptor_name': 'Anti-Inflammatory Agents', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D000893', 'descriptor_name': 'Anti-Inflammatory Agents', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D000893', 'descriptor_name': 'Anti-Inflammatory Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016207', 'descriptor_name': 'Cytokines', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D016207', 'descriptor_name': 'Cytokines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004195', 'descriptor_name': 'Disease Models, Animal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007371', 'descriptor_name': 'Interferon-gamma', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D007371', 'descriptor_name': 'Interferon-gamma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008168', 'descriptor_name': 'Lung', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008168', 'descriptor_name': 'Lung', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008168', 'descriptor_name': 'Lung', 'qualifier_ui': 'Q000821', 'qualifier_name': 'virology', 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008807', 'descriptor_name': 'Mice, Inbred BALB C', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009975', 'descriptor_name': 'Orthomyxoviridae', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009976', 'descriptor_name': 'Orthomyxoviridae Infections', 'qualifier_ui': 'Q000821', 'qualifier_name': 'virology', 'is_major_topic': False}, {'descriptor_ui': 'D009976', 'descriptor_name': 'Orthomyxoviridae Infections', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D009976', 'descriptor_name': 'Orthomyxoviridae Infections', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019936', 'descriptor_name': 'Probiotics', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D019936', 'descriptor_name': 'Probiotics', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D019936', 'descriptor_name': 'Probiotics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015431', 'descriptor_name': 'Weight Loss', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1248/bpb.34.1352', 'pdf_url': 'https://www.jstage.jst.go.jp/article/bpb/34/8/34_8_1352/_pdf', 'source': {'id': 'https://openalex.org/S165235614', 'display_name': 'Biological and Pharmaceutical Bulletin', 'issn_l': '0918-6158', 'issn': ['0918-6158', '1347-5215'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310313382', 'host_organization_name': 'Pharmaceutical Society of Japan', 'host_organization_lineage': ['https://openalex.org/P4310313382'], 'host_organization_lineage_names': ['Pharmaceutical Society of Japan'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/21804232', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1248/bpb.34.1352', 'pdf_url': 'https://www.jstage.jst.go.jp/article/bpb/34/8/34_8_1352/_pdf', 'source': {'id': 'https://openalex.org/S165235614', 'display_name': 'Biological and Pharmaceutical Bulletin', 'issn_l': '0918-6158', 'issn': ['0918-6158', '1347-5215'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310313382', 'host_organization_name': 'Pharmaceutical Society of Japan', 'host_organization_lineage': ['https://openalex.org/P4310313382'], 'host_organization_lineage_names': ['Pharmaceutical Society of Japan'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.84, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 20, 'referenced_works': ['https://openalex.org/W1508547562', 'https://openalex.org/W1778565685', 'https://openalex.org/W1896771111', 'https://openalex.org/W1964953858', 'https://openalex.org/W1992144919', 'https://openalex.org/W1998574278', 'https://openalex.org/W2060171085', 'https://openalex.org/W2075578688', 'https://openalex.org/W2086498998', 'https://openalex.org/W2105315699', 'https://openalex.org/W2106535354', 'https://openalex.org/W2108589639', 'https://openalex.org/W2112714728', 'https://openalex.org/W2136041773', 'https://openalex.org/W2148494803', 'https://openalex.org/W2151295474', 'https://openalex.org/W2158222322', 'https://openalex.org/W2163738297', 'https://openalex.org/W4232504066', 'https://openalex.org/W867443053'], 'related_works': ['https://openalex.org/W3188661910', 'https://openalex.org/W2782428046', 'https://openalex.org/W2564867311', 'https://openalex.org/W2521771323', 'https://openalex.org/W2392672625', 'https://openalex.org/W2387965106', 'https://openalex.org/W2161968779', 'https://openalex.org/W2147113485', 'https://openalex.org/W2003426600', 'https://openalex.org/W1692806112'], 'abstract_inverted_index': {'We': [0], 'investigated': [1], 'whether': [2], 'the': [3, 42, 52, 56, 63, 68, 82, 93, 96, 99, 111, 129, 135, 141, 145, 150, 153, 163, 172], 'oral': [4, 154], 'administration': [5, 155], 'of': [6, 44, 84, 101, 117, 122, 131, 137, 152, 156, 166, 169], 'Bifidobacterium': [7], 'longum': [8], 'BB536': [9, 24, 37, 69, 112, 157, 170], 'could': [10], 'ameliorate': [11], 'influenza': [12], 'virus': [13, 142], '(IFV)': [14], 'infection': [15, 161], 'in': [16, 51, 62, 67, 81, 92, 110, 144, 158, 171], 'a': [17], 'mice': [18], 'model.': [19], 'Mice': [20], 'were': [21, 65, 105], 'orally': [22], 'administrated': [23], 'or': [25], 'saline': [26], 'for': [27], '2': [28], 'weeks': [29], 'and': [30, 47, 90, 103, 124, 134, 162], 'then': [31], 'infected': [32], 'with': [33, 115, 128, 140], 'IFV.': [34, 176], 'Orally': [35], 'administered': [36], 'significantly': [38, 127], 'alleviated': [39], 'symptoms,': [40], 'reduced': [41], 'loss': [43], 'body': [45], 'weight,': [46], 'inhibited': [48], 'viral': [49], 'proliferation': [50], 'lungs': [53, 64, 94], 'relative': [54], 'to': [55, 72], 'control': [57, 73, 118], 'group': [58, 70, 74, 113], 'findings.': [59, 75], 'Histopathological': [60], 'findings': [61], 'improved': [66], 'compared': [71, 114], 'There': [76], 'was': [77], 'no': [78], 'significant': [79], 'difference': [80], 'levels': [83, 100, 121, 136], 'interleukin-6': [85], '(IL-6),': [86], 'interferon-γ': [87], '(IFN-γ),': [88], 'IL-10': [89, 125], 'IL-12p40': [91], 'between': [95], 'groups,': [97], 'but': [98], 'IL-6': [102, 123], 'IFN-γ': [104, 138], 'lower': [106], '(p=0.076,': [107], '0.103,': [108], 'respectively)': [109], 'those': [116], 'group.': [119], 'The': [120], 'correlated': [126, 139], 'values': [130], 'weight': [132], 'loss,': [133], 'titers': [143], 'lungs.': [146], 'These': [147], 'results': [148], 'suggested': [149], 'potential': [151], 'ameliorating': [159], 'IFV': [160], 'possible': [164], 'involvement': [165], 'anti-inflammatory': [167], 'effects': [168, 174], 'anti-infection': [173], 'against': [175]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2105499941', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 4}, {'year': 2022, 'cited_by_count': 10}, {'year': 2021, 'cited_by_count': 15}, {'year': 2020, 'cited_by_count': 9}, {'year': 2019, 'cited_by_count': 4}, {'year': 2017, 'cited_by_count': 3}, {'year': 2016, 'cited_by_count': 4}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 6}], 'updated_date': '2024-12-12T06:20:32.193215', 'created_date': '2016-06-24'}