Title: Protective Effect of Sanshendan Granule on Myocardial Ischemia of Rats Induced by Isoproterenol
Abstract: Objective:Study on the protective effect of Sanshendan granule on myocardial ischemia of rats induced by isoproterenol.Methods: Screen rats of qualified ECG and intragastric administration with the granule.Then prepare myocardial ischemia model in the way of injecting isoproterenol in the abdominal cavity.At last determin the AST,ALT Activities of the serum.Result:AST,ALT activities of serum on the myocardial ischemia model group were significantly higher than those in normal control group(P0.01).And these activities of the serum on the middle dose group as well as low dose group were significantly decreased than those in the model group(P0.01).Moreover,these activities of serum on the high dose group compared with the model group were decreased slightly(P0.05 or P0.01).Conclusion: The Sanshendan granule has a protective function for myocardial ischemia of rats induced by isoproterenol.And the effect may be related to the decrease of serum AST and ALT activities.
Publication Year: 2013
Publication Date: 2013-01-01
Language: en
Type: article
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