Title: Protective effects of salidroside on isoprenaline induced myocardial ischemia in rats
Abstract: AIM:To study the protective effects of salidroside on isoprenaline induced acute myocardial ischemia in rats.METHODS:The model was established by subcutaneous injection(s.c.) of isoprenaline.The change of Electrocardiogram(ECG) was observed.The levels of LDH,CK,SOD and MDA in serum were measured and the cardiac infarction area was examined.RESULTS:Salidroside(6,12,24 mg/kg) could effectively reverse the evident changes of T wave and J point induced by isoproterenol,notably decrease the levels of LDH,CK and MDA and increase the levels of SOD in serum(P0.01,P0.05 vs Model),and significantly reduce the cardiac infarction area(P0.01).CONCLUSION:Salidroside protects rats from acute myocardial ischemia.
Publication Year: 2008
Publication Date: 2008-01-01
Language: en
Type: article
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