Title: Relationship between expression of PS2 protein and ER and PR in breast cancer and its prognostic significance
Abstract:OBJECTIVE:To explore the expression of PS2 in breast cancer, its relationship to ER and PR,and its prognostic significance. METHODS:The expression of PS2 in 110 cases of breast cancer was detected wit...OBJECTIVE:To explore the expression of PS2 in breast cancer, its relationship to ER and PR,and its prognostic significance. METHODS:The expression of PS2 in 110 cases of breast cancer was detected with the immunohistochemical technique (LSAB). RESULTS:Expression of PS2 was found in 39.09% cases of breast cancer,and there was no significant association of its expression with age,P0.05, but its expression in breast cancer was negatively related to the histological grade and axillary lymph node metastasis,P0.05.The expression of PS2 was 48.53% in ER positive group and 23.81% in ER negative group,P=0.01.The expression of PS2 was 49.15% in PR positive group and 27.45% in PR negative group,P=0.02,which was positively related to ER and PR,respectively.CONCLUSION:PS2 is an important marker for predicting prognosis and endocrine treatment in breast cancer.Read More
Publication Year: 2004
Publication Date: 2004-01-01
Language: en
Type: article
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