Publication Information

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'issn_l': '0253-3006', 'issn': ['0253-3006'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4320800525', 'host_organization_name': 'Chinese Medical Association', 'host_organization_lineage': ['https://openalex.org/P4320800525'], 'host_organization_lineage_names': ['Chinese Medical Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W933346801', 'https://openalex.org/W3193984940', 'https://openalex.org/W3144279060', 'https://openalex.org/W3031810427', 'https://openalex.org/W3031506584', 'https://openalex.org/W3030897278', 'https://openalex.org/W3030452432', 'https://openalex.org/W2412318791', 'https://openalex.org/W2406500776', 'https://openalex.org/W2391015955', 'https://openalex.org/W2386479565', 'https://openalex.org/W2376377144', 'https://openalex.org/W2362043032', 'https://openalex.org/W2361056451', 'https://openalex.org/W2358242887', 'https://openalex.org/W2353815412', 'https://openalex.org/W2186627362', 'https://openalex.org/W2027969858', 'https://openalex.org/W2010026085', 'https://openalex.org/W1513677097'], 'abstract_inverted_index': {'目的': [0], '探讨粘附连接复合体中E-钙粘附素和β-连环素(E-cadherin/β-catenin)以及相关基因基质金属蛋白酶-7(MMP-7)在肾母细胞瘤中的表达及其意义.方法': [1], '采用免疫组织化学方法,对经过石蜡包埋的30例肾母细胞瘤和9例非肿瘤肾组织标本进行检测.结果': [2], 'E-cadherin在肾母细胞瘤组织中有表达缺失且在预后良好型组(FH)中的表达高于预后不良型组(UH),差异有统计学意义(P＜0.05).β-catenin、MMP-7在非肿瘤肾组织中低表达,两者在肾母细胞瘤组织中高表达,在Ⅲ～Ⅳ期组织中表达高于Ⅰ～Ⅱ期,两者在FH组中和UH组中的表达差异有统计学意义(P＜0.05),且β-catenin与MMP-7的表达水平呈正相关(r=0.66,P＜0.01).结论': [3], 'E-cadherin蛋白的阳性表达缺失参与了肾母细胞瘤的恶性转化,而β-catenin和MMP-7的阳性表达促进了肾母细胞瘤的侵袭转移。': [4]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3030579153', 'counts_by_year': [], 'updated_date': '2024-12-15T16:36:43.990515', 'created_date': '2020-06-05'}