Publication Information

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False, 'landing_page_url': 'http://rs.yiigle.com/CN115989201009/629519.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764489546', 'display_name': 'Zhonghua shiyan yanke zazhi', 'issn_l': '2095-0160', 'issn': ['2095-0160'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4320800525', 'host_organization_name': 'Chinese Medical Association', 'host_organization_lineage': ['https://openalex.org/P4320800525'], 'host_organization_lineage_names': ['Chinese Medical Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.71}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W933346801', 'https://openalex.org/W3193984940', 'https://openalex.org/W3144279060', 'https://openalex.org/W3036830918', 'https://openalex.org/W3032322312', 'https://openalex.org/W3030579153', 'https://openalex.org/W2441084609', 'https://openalex.org/W2406500776', 'https://openalex.org/W2393540321', 'https://openalex.org/W2386479565', 'https://openalex.org/W2376377144', 'https://openalex.org/W2363044355', 'https://openalex.org/W2361150604', 'https://openalex.org/W2361056451', 'https://openalex.org/W2358242887', 'https://openalex.org/W2353815412', 'https://openalex.org/W2162550420', 'https://openalex.org/W2027969858', 'https://openalex.org/W1977932678', 'https://openalex.org/W1513677097'], 'abstract_inverted_index': {'目的': [0], '研究E-cadherin及β-catenin在泪腺多形性腺瘤和腺样囊性癌中的表达.方法': [1], '选取经病理检查确诊为泪腺多形性腺瘤的患者11例11眼和腺样囊性癌的患者6例6眼,分别行E-cadherin和β-catenin免疫组织化学染色.选取泪腺脱垂患者的泪腺组织6例作为正常对照组.结果': [2], '正常泪腺组织中E-cadherin呈强阳性表达,主要位于细胞膜;而在泪腺多形性腺瘤中E-cadherin呈弱阳性表达,主要位于细胞质.E-cadherin在腺样囊性癌中未见表达.3组中E-cadherin阳性表达的样本数差异有统计学意义(H=16.492,P=0.000);正常泪腺组E-cadherin阳性表达的样本数明显高于多形性腺瘤组和腺样囊性癌组,差异均有统计学意义(U=-3.561,P=0.000;U=-3.108,P=0.002),多形性腺瘤组中E-cadherin阳性表达的样本数明显高于腺样囊性癌组,差异有统计学意义(U=-2.147,P=0.032).正常泪腺β-catenin细胞膜呈中度或强阳性表达,多形性腺瘤和腺样囊性癌中β-catenin的表达较正常泪腺组织表达阳性程度差异无统计学意义(P＞0.05),腺样囊性癌组中β-catenin细胞核阳性的比例(33.3%,2/6)较多形性腺瘤组(72.7%,7/11)低.结论': [3], 'E-cadherin表达的下降是参与泪腺上皮性肿瘤发生及癌变的重要因素,而E-cadherin的进一步下降甚至缺失,以及β-catenin的核转位可能是参与泪腺多形性腺瘤恶性转化的因素之一。': [4]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3031506584', 'counts_by_year': [], 'updated_date': '2024-12-14T12:06:18.167423', 'created_date': '2020-06-05'}