Publication Information

{'id': 'https://openalex.org/W3030108708', 'doi': 'https://doi.org/10.3760/cma.j.issn.1001-9030.2014.06.048', 'title': 'Influences of arsenic trioxide on lung cancer cell line NCI-H520', 'display_name': 'Influences of arsenic trioxide on lung cancer cell line NCI-H520', 'publication_year': 2014, 'publication_date': '2014-06-08', 'ids': {'openalex': 'https://openalex.org/W3030108708', 'doi': 'https://doi.org/10.3760/cma.j.issn.1001-9030.2014.06.048', 'mag': '3030108708'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'http://rs.yiigle.com/CN42121320143106/479358.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764660617', 'display_name': 'Zhonghua shiyan waike zazhi', 'issn_l': '1001-9030', 'issn': ['1001-9030'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4320800525', 'host_organization_name': 'Chinese Medical Association', 'host_organization_lineage': ['https://openalex.org/P4320800525'], 'host_organization_lineage_names': ['Chinese Medical Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': [], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5102183437', 'display_name': 'Tan Yuan', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210113613', 'display_name': 'Fifth Affiliated Hospital of Zhengzhou University', 'ror': 'https://ror.org/01wfgh551', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210113613']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Tan Yuan', 'raw_affiliation_strings': ['Department of Respiratory Diseases, the Fifth Affiliated Hospital of Zhengzhou University,Zhengzhou 450052, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Respiratory Diseases, the Fifth Affiliated Hospital of Zhengzhou University,Zhengzhou 450052, China', 'institution_ids': ['https://openalex.org/I4210113613']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5100623845', 'display_name': 'Hongyun Li', 'orcid': 'https://orcid.org/0000-0001-5091-9064'}, 'institutions': [{'id': 'https://openalex.org/I4210113613', 'display_name': 'Fifth Affiliated Hospital of Zhengzhou University', 'ror': 'https://ror.org/01wfgh551', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210113613']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Hongyun Li', 'raw_affiliation_strings': ['Department of Respiratory Diseases, the Fifth Affiliated Hospital of Zhengzhou University,Zhengzhou 450052, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Respiratory Diseases, the Fifth Affiliated Hospital of Zhengzhou University,Zhengzhou 450052, China', 'institution_ids': ['https://openalex.org/I4210113613']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 66}, 'biblio': {'volume': '31', 'issue': '06', 'first_page': '1292', 'last_page': '1293'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11559', 'display_name': 'Retinoids in leukemia and cellular processes', 'score': 0.9886, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11559', 'display_name': 'Retinoids in leukemia and cellular processes', 'score': 0.9886, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10274', 'display_name': 'Synthesis and biological activity', 'score': 0.9188, 'subfield': {'id': 'https://openalex.org/subfields/1605', 'display_name': 'Organic Chemistry'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/arsenic-trioxide', 'display_name': 'Arsenic Trioxide', 'score': 0.99214196}], 'concepts': [{'id': 'https://openalex.org/C2780386689', 'wikidata': 'https://www.wikidata.org/wiki/Q7739', 'display_name': 'Arsenic trioxide', 'level': 3, 'score': 0.99214196}, {'id': 'https://openalex.org/C190283241', 'wikidata': 'https://www.wikidata.org/wiki/Q14599311', 'display_name': 'Apoptosis', 'level': 2, 'score': 0.7149329}, {'id': 'https://openalex.org/C502230775', 'wikidata': 'https://www.wikidata.org/wiki/Q871', 'display_name': 'Arsenic', 'level': 2, 'score': 0.5941579}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.5865927}, {'id': 'https://openalex.org/C2776256026', 'wikidata': 'https://www.wikidata.org/wiki/Q47912', 'display_name': 'Lung cancer', 'level': 2, 'score': 0.5057392}, {'id': 'https://openalex.org/C553184892', 'wikidata': 'https://www.wikidata.org/wiki/Q1141429', 'display_name': 'Flow cytometry', 'level': 2, 'score': 0.48057556}, {'id': 'https://openalex.org/C62112901', 'wikidata': 'https://www.wikidata.org/wiki/Q189159', 'display_name': 'Cell growth', 'level': 2, 'score': 0.44572863}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.3832659}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.36249262}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.25366724}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.25287002}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.21080852}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.16905701}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.064371645}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'http://rs.yiigle.com/CN42121320143106/479358.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764660617', 'display_name': 'Zhonghua shiyan waike zazhi', 'issn_l': '1001-9030', 'issn': ['1001-9030'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4320800525', 'host_organization_name': 'Chinese Medical Association', 'host_organization_lineage': ['https://openalex.org/P4320800525'], 'host_organization_lineage_names': ['Chinese Medical Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.76, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3032449367', 'https://openalex.org/W2464487927', 'https://openalex.org/W2392059173', 'https://openalex.org/W2391404431', 'https://openalex.org/W2389890371', 'https://openalex.org/W2388994989', 'https://openalex.org/W2387311356', 'https://openalex.org/W2386804046', 'https://openalex.org/W2383301047', 'https://openalex.org/W2377303742', 'https://openalex.org/W2374547061', 'https://openalex.org/W2367562620', 'https://openalex.org/W2367271670', 'https://openalex.org/W2364232049', 'https://openalex.org/W2363468326', 'https://openalex.org/W2361485389', 'https://openalex.org/W2358367877', 'https://openalex.org/W2355562449', 'https://openalex.org/W2351788900', 'https://openalex.org/W2350365243'], 'abstract_inverted_index': {'Objective': [0], 'To': [1], 'explore': [2], 'the': [3, 8, 61, 68, 164], 'proliferation': [4, 50, 147], 'inhibition': [5, 148], 'effect': [6, 10, 149], 'and': [7, 40, 79, 90, 104, 125, 129, 136, 139, 142, 144], 'apoptosis-promoting': [9, 116], 'of': [11, 32, 51, 70, 85, 99, 120, 150, 167], 'arsenic': [12, 33, 74, 100, 111, 151], 'trioxide': [13, 34, 75, 101, 112, 152, 160, 174], 'at': [14, 35, 76], 'different': [15, 18, 77, 97], 'concentrations': [16, 31, 78, 98], 'with': [17, 29, 73, 96, 123], 'action': [19, 80], 'time': [20], 'points.Methods': [21], 'Human': [22], 'lung': [23], 'cancer': [24], 'NCI-H520': [25, 93, 121, 168], 'cells': [26, 44, 52, 71, 94, 122], 'were': [27, 45, 88], 'treated': [28, 72, 95], 'serial': [30], '1.0,2.0,3.0,6.0,10.0': [36], 'μmol/L': [37, 110, 127], 'for': [38, 102], '24,48': [39, 103], '72': [41, 105, 130], 'h.The': [42], 'untreated': [43], 'used': [46, 65], 'as': [47], 'negative': [48], 'control.The': [49], 'was': [53, 64, 134], 'tested': [54], 'by': [55], 'methyl': [56], 'thiazol': [57], 'tetrazolium': [58], '(MTT)': [59], 'assay,and': [60], 'flow': [62], 'cytometry': [63], 'to': [66], 'measure': [67], 'apoptosis': [69, 132, 165], 'times.Results': [81], 'The': [82, 146], 'F': [83], 'values': [84], 'One-Way': [86], 'ANOVA': [87], '109.9,139.7': [89], '191.1': [91], 'after': [92, 118], 'h': [106], '(P': [107], '＜': [108], '0.05).1.0': [109], 'showed': [113], 'no': [114], 'obvious': [115], 'effect,but': [117], 'treatment': [119], '2.0,3.0': [124], '6.0': [126], 'for24,48': [128], 'h,the': [131], 'rate': [133, 166], '5.92％,8.91％': [135], '15.10％;': [137], '7.55％,14.31％': [138], '35.17％': [140], ';': [141], '19.8％,39.87％': [143], '63.66％,respectively.Conclusion': [145], 'is': [153], 'increased': [154], 'in': [155], 'a': [156], 'time-and': [157], 'concentration-dependent': [158], 'manner.Besides,arsenic': [159], 'can': [161], 'significantly': [162], 'increase': [163], 'cells.\r\n\r\nKey': [169], 'words:': [170], '\r\nLung': [171], 'cancer;\xa0': [172], 'Arsenic': [173], ';\xa0': [175], 'Proliferation': [176], 'inhibition;\xa0': [177], 'Apoptosis': [178]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3030108708', 'counts_by_year': [], 'updated_date': '2024-12-15T08:16:30.509978', 'created_date': '2020-06-05'}