Publication Information

{'id': 'https://openalex.org/W2351788900', 'doi': None, 'title': 'Effect of Arsenic Trioxide on Cell Cycle and Apoptosis of Multidrug Resistant K562/A02 Cell Line', 'display_name': 'Effect of Arsenic Trioxide on Cell Cycle and Apoptosis of Multidrug Resistant K562/A02 Cell Line', 'publication_year': 2012, 'publication_date': '2012-01-01', 'ids': {'openalex': 'https://openalex.org/W2351788900', 'mag': '2351788900'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://en.cnki.com.cn/Article_en/CJFDTOTAL-SWCX201215013.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764952023', 'display_name': 'Xiandai shengwu yixue jinzhan', 'issn_l': '1673-6273', 'issn': ['1673-6273'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4361727479', 'host_organization_name': 'Heilongjiang Red Cross Society', 'host_organization_lineage': ['https://openalex.org/P4361727479'], 'host_organization_lineage_names': ['Heilongjiang Red Cross Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': [], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5103811381', 'display_name': 'Sun Hai-ying', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210106614', 'display_name': 'Affiliated Hospital of Xuzhou Medical College', 'ror': 'https://ror.org/011xhcs96', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210106614']}, {'id': 'https://openalex.org/I177388780', 'display_name': 'Xuzhou Medical College', 'ror': 'https://ror.org/04fe7hy80', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I177388780']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Sun Hai-ying', 'raw_affiliation_strings': ['2 Department of Hematology,Affiliated hospital of Xuzhou medical college,Jiangsu,Xuzhou 221006,China)'], 'affiliations': [{'raw_affiliation_string': '2 Department of Hematology,Affiliated hospital of Xuzhou medical college,Jiangsu,Xuzhou 221006,China)', 'institution_ids': ['https://openalex.org/I4210106614', 'https://openalex.org/I177388780']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5103811381'], 'corresponding_institution_ids': ['https://openalex.org/I4210106614', 'https://openalex.org/I177388780'], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 64}, 'biblio': {'volume': None, 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11559', 'display_name': 'Retinoids in leukemia and cellular processes', 'score': 0.9833, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11559', 'display_name': 'Retinoids in leukemia and cellular processes', 'score': 0.9833, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/arsenic-trioxide', 'display_name': 'Arsenic Trioxide', 'score': 0.9832362}, {'id': 'https://openalex.org/keywords/k562-cells', 'display_name': 'K562 cells', 'score': 0.49293017}, {'id': 'https://openalex.org/keywords/trioxide', 'display_name': 'Trioxide', 'score': 0.4241865}], 'concepts': [{'id': 'https://openalex.org/C2780386689', 'wikidata': 'https://www.wikidata.org/wiki/Q7739', 'display_name': 'Arsenic trioxide', 'level': 3, 'score': 0.9832362}, {'id': 'https://openalex.org/C190283241', 'wikidata': 'https://www.wikidata.org/wiki/Q14599311', 'display_name': 'Apoptosis', 'level': 2, 'score': 0.80049163}, {'id': 'https://openalex.org/C553184892', 'wikidata': 'https://www.wikidata.org/wiki/Q1141429', 'display_name': 'Flow cytometry', 'level': 2, 'score': 0.6386031}, {'id': 'https://openalex.org/C29537977', 'wikidata': 'https://www.wikidata.org/wiki/Q188941', 'display_name': 'Cell cycle', 'level': 3, 'score': 0.5788332}, {'id': 'https://openalex.org/C502230775', 'wikidata': 'https://www.wikidata.org/wiki/Q871', 'display_name': 'Arsenic', 'level': 2, 'score': 0.5728021}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.56045705}, {'id': 'https://openalex.org/C171122931', 'wikidata': 'https://www.wikidata.org/wiki/Q6324626', 'display_name': 'K562 cells', 'level': 3, 'score': 0.49293017}, {'id': 'https://openalex.org/C2776415932', 'wikidata': 'https://www.wikidata.org/wiki/Q48743', 'display_name': 'Western blot', 'level': 3, 'score': 0.44485798}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.43523332}, {'id': 'https://openalex.org/C2778515548', 'wikidata': 'https://www.wikidata.org/wiki/Q3666421', 'display_name': 'Trioxide', 'level': 3, 'score': 0.4241865}, {'id': 'https://openalex.org/C154317977', 'wikidata': 'https://www.wikidata.org/wiki/Q376266', 'display_name': 'Cytotoxic T cell', 'level': 3, 'score': 0.41522464}, {'id': 'https://openalex.org/C62112901', 'wikidata': 'https://www.wikidata.org/wiki/Q189159', 'display_name': 'Cell growth', 'level': 2, 'score': 0.41399485}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.3640694}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.3493892}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.33045053}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.26916838}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.22097713}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.043047488}, {'id': 'https://openalex.org/C518881349', 'wikidata': 'https://www.wikidata.org/wiki/Q682', 'display_name': 'Sulfur', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://en.cnki.com.cn/Article_en/CJFDTOTAL-SWCX201215013.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764952023', 'display_name': 'Xiandai shengwu yixue jinzhan', 'issn_l': '1673-6273', 'issn': ['1673-6273'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4361727479', 'host_organization_name': 'Heilongjiang Red Cross Society', 'host_organization_lineage': ['https://openalex.org/P4361727479'], 'host_organization_lineage_names': ['Heilongjiang Red Cross Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3032224011', 'https://openalex.org/W3030108708', 'https://openalex.org/W2393299638', 'https://openalex.org/W2392320026', 'https://openalex.org/W2391404431', 'https://openalex.org/W2389890371', 'https://openalex.org/W2388994989', 'https://openalex.org/W2387311356', 'https://openalex.org/W2385445431', 'https://openalex.org/W2383301047', 'https://openalex.org/W2377303742', 'https://openalex.org/W2373968803', 'https://openalex.org/W2368490024', 'https://openalex.org/W2364232049', 'https://openalex.org/W2363988941', 'https://openalex.org/W2358367877', 'https://openalex.org/W2355562449', 'https://openalex.org/W2350365243', 'https://openalex.org/W2349433192', 'https://openalex.org/W2349408089'], 'abstract_inverted_index': {'Objective:': [0], 'To': [1], 'explore': [2], 'the': [3, 47, 68, 77], 'effect': [4], 'of': [5, 13, 46, 50, 70, 79, 93], 'arsenic': [6, 26, 33, 64, 88], 'trioxide': [7, 65, 89], 'on': [8, 103], 'cell': [9, 42, 97], 'cycle': [10, 43], 'and': [11, 16, 41, 75, 95], 'apoptosis': [12, 40, 92], 'K562/A02': [14, 22, 94], 'cells': [15, 72], 'its': [17, 101], 'possible': [18], 'mechanism.Methods:': [19], 'Adriamycin(Adr)': [20], 'resistant': [21], 'were': [23], 'treated': [24], 'with': [25, 62], 'trioxide(non-cytotoxic': [27], 'concentration': [28], 'at': [29], '4.0υmol/L,5.0υmol/L)': [30], 'or': [31], 'without': [32], 'trioxide(control),flow': [34], 'cytometry': [35], 'was': [36, 55], 'used': [37], 'to': [38, 90], 'evaluate': [39], 'distribution,and': [44], 'change': [45], 'expression': [48], 'level': [49], 'NF-κBp65': [51, 80, 104], 'protein': [52, 81, 105], 'in': [53, 73, 82, 100], 'nucleus': [54], 'detected': [56], 'by': [57], 'western': [58], 'blot.Results:': [59], 'As': [60], 'compared': [61], 'control': [63], 'significantly': [66], 'increased': [67], 'rate': [69], 'apoptosis,arrested': [71], 'G0/G1phase': [74], 'reduced': [76], 'levels': [78], 'nucleus(allP0.05).Conclusion:': [83], 'The': [84], 'underlying': [85], 'mechanism': [86], 'for': [87], 'promote': [91], 'suppress': [96], 'proliferation': [98], 'lies': [99], 'impact': [102], 'expression.': [106]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2351788900', 'counts_by_year': [], 'updated_date': '2024-12-15T14:11:16.111302', 'created_date': '2016-06-24'}