Title: Efficacy Observation of Human Immune Globulin in the Treatment of Severe Pneumonia with Intravenous Infusion
Abstract: OBJECTIVE:To observe efficacy of human immune globulin(IHIG)via i.v.in the treatment of severe pneumonia.METHODS:84 patients with severe pneumonia in respiratory department were divided into treatment group(44 cases)and control group(40 cases.) Both groups were given conventional therapy,such as inhaling oxygen,clearing phlegm,antiinfection therapy.InTarHreIyat Gi mn2ef0en1tct i~gor5no0 u0sp c omrwgeas.(k CgdiPvI1iS.dde)ds1.ci onrCtiloin ngsi ucsabolfg trswoyuamrpep t Aow amassn dua snsedud b stigorg oneusv paa lnBud.a t ceTl ithnheieyc aslwe eevfreferii ctaayd cdoyif t iiwonenfraeelc ltcyio ognmi.p vaeRrneel daI tiHboIentGs wh1eiep0n 0o f2~ 2sgc0ro0or uep msc.gh a.Cnkliggneis1c alw.d itphu1 l eafmfnoidcacy was compared before and after treatment.RESULTS:Relieve time of cough and expectoration and sputum bacterial conversion time in treatment group were shorter than in control group.The effective rate of treatment group was 63.6%,which was better than that of control group significantly(32.5%,P0.05).Xray absorption time of inflammation had no significant difference between subgroup A and control group(P0.05),while there was significant difference between subgroup B and control group(P 0.05.) After treatment the average CPIS score of treatment group was significantly lower than before treatment(P0.05.) The changes of CPIS score closely linked to efficacy before and after treatment.CONCLUSION:Adjunctive therapy of IHIG shows significant efficacy in the treatment of severe pneumonia,prevents inflammation out of control and reduce mortality.
Publication Year: 2010
Publication Date: 2010-01-01
Language: en
Type: article
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