Title: The efficacy observation about intravenous gamma globulin treatment of severe bronchiolitis
Abstract: Objective:To observe the clinical efficacy and safety about intravenous gamma globulin(IVIG) treatment of severe bronchiolitis.Methods:64 children with severe bronchiolitis were divided into treatment group 33 cases and 31 cases of the control group randomly.Both groups were given anti-infective,anti-virus,cough,phlegm,asthma,oxygen,application of adrenal glucocorticoid comprehensive treatment.Based on it,the IVIG 400 mg/(kg·d) was administered in the treatment group,once a day,three days used in conjunction.To observe the efficacy and adverse reactions,and measured the level of immunoglobulin.Results:The two groups in cough,asthma,breathing difficulties and wheezing lungs sound disap pear time and hospitalization was more significant difference(P0.01) .The total efficiency of the two groups were significantly different(P0.01) .After the application of gamma globulin,the level of IgG were significantly higher(P0.01) ,adverse reactions between the two groups were not significant difference(P0.05) .Conclusion:IVIG treatment with severe bronchiolitis may shorten the course,the exact efficacy,safety,no adverse reactions,can be applied in clinical.
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
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