Title: The application of multi-serum combined detection of diabetic nephropathy
Abstract: Objective To investigate the serum cystatin C(CysC),retinol binding protein(RBP) and β2-microglobulin(β2-MG) of the combined detection of clinical diagnosis of diabetic nephropathy.Methods The serum CysC,RBP,β2-MG,blood urea(Sur) and serum creatinine(Scr) levels in 100 cases of diabete patients and 92 patients with diabetic nephropathy were detected,and 100 healthy people were chosen as the control group.Results The levels of CysC,RBP,β2-MG,Sur and Scr in patients with diabetic nephropathy were significantly higher than the diabetes group and the control group(P0.01).And the positive ratio of serum CysC,RBP,β2-MG were significantly higher than that of the Sur,Scr.Combined detection was better than the first three single test.Conclusion The levels of CysC,RBP,β2-MG and as well as the joint detection of the three in patients with diabetic nephropathy were statistically significant compared with the control group.The serum β2-MG level in diabetic nephropathy patients was higher than that of the healthy controls,showing an ascending trend.Moreover,the serum CysC,RBP,β2-MG combined detection can improve the successful detection chance of early diabetic nephropathy.
Publication Year: 2011
Publication Date: 2011-01-01
Language: en
Type: article
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