Title: Evaluation of cystatin C in diabetic nephropathy patients
Abstract: Objective: To evaluate the level and significance of serum cystatin C(Cys C) in diabetic nephropathy patients.Methods:The levels of serum CysC,carnine and β2-microglobulin(β2-MG) in 85 cases of diabetic mellitus(35 cases with normal renal function,28 cases with mild renal damage,12 cases with moderate renal damage,10 cases with severe renal damage) and 50 healthy subjects(control group) were determined by scattering turbidimetry,enzyme method and radioimmunity method,respectively.Results:The levels of serum CysC and β2-MG significantly increased along with the severity of renal damage.The levels of serum CysC and β2-MG in mild renal damage group were significantly higher than those in control group(P0.05),however,serum carnine was just increased in moderate and severe renal damage group(P0.05).Conclusion:Serum CysC is a good assistant diagnostic index for early renal damage in diabetic nephropathy patients.
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
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