Title: Donepezil alone vs donepezil combined with Gingko biloba extract in treatment of Alzheimer disease
Abstract:AIM: To compare the effects of donepezil alone and donepezil combined with Gingko biloba extract in treatment of Alzheimer disease (AD). METHODS: Forty-two patients with AD were divided into two group...AIM: To compare the effects of donepezil alone and donepezil combined with Gingko biloba extract in treatment of Alzheimer disease (AD). METHODS: Forty-two patients with AD were divided into two groups. Donepezil alone group of 20 patients (M 17, F 3; age (70±s7) a) received donepezil 5 mg, po, qd for 12 wk; donepezil combined with Gingko biloba extract group of 22 patients (M 13, F 9; age (79±6) a) received donepezil 5 mg, po, qd for 12 wk and Gingko bilba extract 80 mg, po, tid for 12 wk. Effects were evaluated with MMSE and ADL. RESULTS: The total clinical effective rates were 60 % for donepezil alone group and 73 % for donepezil combined with Gingko biloa extract group. There was no significant difference between two groups(P0.05). CONCLUSION: Donepezil is a safe and effective drug in treatment of AD. The effect of donepezil combined with Gingko biloba extract is same to that of donepezil alone in treatment of AD.Read More
Publication Year: 2004
Publication Date: 2004-01-01
Language: en
Type: article
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Cited By Count: 2
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