Publication Information

{'id': 'https://openalex.org/W3186952914', 'doi': 'https://doi.org/10.1590/1806-9282.67.02.20200378', 'title': "Dengzhan shengmai capsule combined with donepezil hydrochloride in the treatment of Alzheimer's disease: preliminary findings, randomized and controlled clinical trial", 'display_name': "Dengzhan shengmai capsule combined with donepezil hydrochloride in the treatment of Alzheimer's disease: preliminary findings, randomized and controlled clinical trial", 'publication_year': 2021, 'publication_date': '2021-02-01', 'ids': {'openalex': 'https://openalex.org/W3186952914', 'doi': 'https://doi.org/10.1590/1806-9282.67.02.20200378', 'mag': '3186952914', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/34287475'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1590/1806-9282.67.02.20200378', 'pdf_url': 'https://www.scielo.br/j/ramb/a/jhfpX4zTyfKKcJfLVyPmzYk/?lang=en&format=pdf', 'source': {'id': 'https://openalex.org/S11235429', 'display_name': 'Revista da Associação Médica Brasileira', 'issn_l': '0104-4230', 'issn': ['0104-4230', '1806-9282'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311978', 'host_organization_name': 'Brazilian Medical Association', 'host_organization_lineage': ['https://openalex.org/P4310311978'], 'host_organization_lineage_names': ['Brazilian Medical Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://www.scielo.br/j/ramb/a/jhfpX4zTyfKKcJfLVyPmzYk/?lang=en&format=pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5084637151', 'display_name': 'Pan Huang', 'orcid': 'https://orcid.org/0000-0002-5927-0369'}, 'institutions': [{'id': 'https://openalex.org/I4210114339', 'display_name': 'Deyang Stomatological Hospital', 'ror': 'https://ror.org/02hd7d161', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210114339']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Pan Huang', 'raw_affiliation_strings': ['People1s Hospital of DeYang City, Department of Neurology - DeYang, China.'], 'affiliations': [{'raw_affiliation_string': 'People1s Hospital of DeYang City, Department of Neurology - DeYang, China.', 'institution_ids': ['https://openalex.org/I4210114339']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5053599391', 'display_name': 'Xiaoying He', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210086248', 'display_name': 'Affiliated Hospital of Southwest Medical University', 'ror': 'https://ror.org/0014a0n68', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210086248']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Xiao-Ying He', 'raw_affiliation_strings': ['The Affiliated Hospital of Southwest Medical University, Department of Neurology - Luzhou, China.'], 'affiliations': [{'raw_affiliation_string': 'The Affiliated Hospital of Southwest Medical University, Department of Neurology - Luzhou, China.', 'institution_ids': ['https://openalex.org/I4210086248']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5088539918', 'display_name': 'Min Xu', 'orcid': 'https://orcid.org/0000-0001-8187-7637'}, 'institutions': [{'id': 'https://openalex.org/I4210165691', 'display_name': "Fuyang Second People's Hospital", 'ror': 'https://ror.org/00e52k684', 'country_code': 'CN', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210165691']}], 'countries': ['CN'], 'is_corresponding': False, 'raw_author_name': 'Min Xu', 'raw_affiliation_strings': ["The second People's Hospital of DeYang City, Department of Neurology - DeYang, China"], 'affiliations': [{'raw_affiliation_string': "The second People's Hospital of DeYang City, Department of Neurology - DeYang, China", 'institution_ids': ['https://openalex.org/I4210165691']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.306, 'has_fulltext': False, 'cited_by_count': 9, 'citation_normalized_percentile': {'value': 0.754601, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 86, 'max': 87}, 'biblio': {'volume': '67', 'issue': '2', 'first_page': '190', 'last_page': '194'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10086', 'display_name': "Alzheimer's disease research and treatments", 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10086', 'display_name': "Alzheimer's disease research and treatments", 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T14144', 'display_name': 'Neurological Disease Mechanisms and Treatments', 'score': 0.9947, 'subfield': {'id': 'https://openalex.org/subfields/2808', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12023', 'display_name': 'Cholinesterase and Neurodegenerative Diseases', 'score': 0.9934, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/capsule', 'display_name': 'Capsule', 'score': 0.5922415}], 'concepts': [{'id': 'https://openalex.org/C2780904820', 'wikidata': 'https://www.wikidata.org/wiki/Q415081', 'display_name': 'Donepezil', 'level': 4, 'score': 0.8094839}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.74083734}, {'id': 'https://openalex.org/C2778778583', 'wikidata': 'https://www.wikidata.org/wiki/Q147768', 'display_name': 'Capsule', 'level': 2, 'score': 0.5922415}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.52121484}, {'id': 'https://openalex.org/C90924648', 'wikidata': 'https://www.wikidata.org/wiki/Q120569', 'display_name': 'Gastroenterology', 'level': 1, 'score': 0.46050048}, {'id': 'https://openalex.org/C100480397', 'wikidata': 'https://www.wikidata.org/wiki/Q7836899', 'display_name': 'Treatment and control groups', 'level': 2, 'score': 0.44217986}, {'id': 'https://openalex.org/C168563851', 'wikidata': 'https://www.wikidata.org/wiki/Q1436668', 'display_name': 'Randomized controlled trial', 'level': 2, 'score': 0.43831533}, {'id': 'https://openalex.org/C535046627', 'wikidata': 'https://www.wikidata.org/wiki/Q30612', 'display_name': 'Clinical trial', 'level': 2, 'score': 0.41560167}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.26232368}, {'id': 'https://openalex.org/C2779483572', 'wikidata': 'https://www.wikidata.org/wiki/Q83030', 'display_name': 'Dementia', 'level': 3, 'score': 0.17520651}, {'id': 'https://openalex.org/C59822182', 'wikidata': 'https://www.wikidata.org/wiki/Q441', 'display_name': 'Botany', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000544', 'descriptor_name': 'Alzheimer Disease', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D004365', 'descriptor_name': 'Drugs, Chinese Herbal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000544', 'descriptor_name': 'Alzheimer Disease', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D002800', 'descriptor_name': 'Cholinesterase Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003071', 'descriptor_name': 'Cognition', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000077265', 'descriptor_name': 'Donepezil', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004311', 'descriptor_name': 'Double-Blind Method', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004365', 'descriptor_name': 'Drugs, Chinese Herbal', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1590/1806-9282.67.02.20200378', 'pdf_url': 'https://www.scielo.br/j/ramb/a/jhfpX4zTyfKKcJfLVyPmzYk/?lang=en&format=pdf', 'source': {'id': 'https://openalex.org/S11235429', 'display_name': 'Revista da Associação Médica Brasileira', 'issn_l': '0104-4230', 'issn': ['0104-4230', '1806-9282'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311978', 'host_organization_name': 'Brazilian Medical Association', 'host_organization_lineage': ['https://openalex.org/P4310311978'], 'host_organization_lineage_names': ['Brazilian Medical Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/476a1beefdfc4d2d96f0f5566b1c9beb', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/34287475', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1590/1806-9282.67.02.20200378', 'pdf_url': 'https://www.scielo.br/j/ramb/a/jhfpX4zTyfKKcJfLVyPmzYk/?lang=en&format=pdf', 'source': {'id': 'https://openalex.org/S11235429', 'display_name': 'Revista da Associação Médica Brasileira', 'issn_l': '0104-4230', 'issn': ['0104-4230', '1806-9282'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311978', 'host_organization_name': 'Brazilian Medical Association', 'host_organization_lineage': ['https://openalex.org/P4310311978'], 'host_organization_lineage_names': ['Brazilian Medical Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.78, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 13, 'referenced_works': ['https://openalex.org/W1957558887', 'https://openalex.org/W1970259736', 'https://openalex.org/W1974743752', 'https://openalex.org/W1993775827', 'https://openalex.org/W2000536660', 'https://openalex.org/W2014386715', 'https://openalex.org/W2018435435', 'https://openalex.org/W2079975961', 'https://openalex.org/W2080225612', 'https://openalex.org/W2157498409', 'https://openalex.org/W2809516213', 'https://openalex.org/W2809744404', 'https://openalex.org/W3005713147'], 'related_works': ['https://openalex.org/W4386466796', 'https://openalex.org/W4300703342', 'https://openalex.org/W4243835735', 'https://openalex.org/W3004549232', 'https://openalex.org/W2746912932', 'https://openalex.org/W2387684281', 'https://openalex.org/W2384834241', 'https://openalex.org/W2358172777', 'https://openalex.org/W2053254879', 'https://openalex.org/W2027037947'], 'abstract_inverted_index': {'SUMMARY': [0], 'OBJECTIVE:': [1], 'To': [2], 'observe': [3], 'the': [4, 65, 82, 93, 97, 105, 114, 128, 132, 141, 168, 177, 212, 221], 'effects': [5], 'of': [6, 30, 91, 96, 126, 163, 215, 223], 'Dengzhan': [7, 71, 200], 'Shengmai': [8, 72, 201], 'capsule': [9, 73, 202], 'combined': [10, 203], 'with': [11, 24, 33, 194, 204, 217], 'donepezil': [12, 57, 205], 'hydrochloride': [13, 58, 206], 'on': [14, 81], 'cognitive': [15, 209], 'function,': [16], 'daily': [17], 'living': [18, 213], 'ability,': [19], 'and': [20, 43, 64, 88, 102, 109, 123, 140, 160, 176, 196, 211, 227, 229], 'safety': [21], 'in': [22, 131, 167], 'patients': [23, 32, 216], "Alzheimer's": [25, 34, 218], 'disease.': [26], 'METHODS:': [27], 'A': [28], 'total': [29], '294': [31], 'disease': [35], 'were': [36, 154, 171], 'randomly': [37], 'divided': [38], 'into': [39], 'a': [40, 44, 62, 78], 'treatment': [41, 66, 98, 133, 169], 'group': [42, 53, 67, 99, 134, 143, 170, 179], 'control': [45, 52, 83, 106, 142, 178], 'group,': [46, 107], '147': [47], 'cases': [48], 'each': [49], 'group.': [50, 84], 'The': [51, 111, 149], 'was': [54, 68, 100, 135, 144, 180, 191], 'given': [55, 69], 'oral': [56, 70], '5': [59], 'mg': [60], 'once': [61], 'day,': [63, 79], '0.36': [74], 'g': [75], 'three': [76], 'times': [77], 'based': [80], 'RESULTS:': [85], 'At': [86, 121, 158], '3': [87, 122, 159], '6': [89, 124, 161], 'months': [90, 125, 162], 'treatment,': [92, 127, 164], 'ADAS-cog': [94, 189], 'score': [95, 190], '48.69±6.23': [101], '44.24±5.53;': [103], 'for': [104], '45.48±5.94': [108], '41.57±5.10.': [110], 'difference': [112], 'between': [113, 151], 'two': [115], 'groups': [116, 153], 'is': [117], 'statistically': [118, 155], 'significant': [119, 156], '(p<0.05).': [120, 157], 'NO': [129, 195, 226], 'level': [130], '(46.28±6.68)': [136], 'umol/l,': [137, 139, 146], '(43.55±7.92)': [138], '(42.95±7.92)': [145], '(38.89±5.93)': [147], 'umol/l.': [148], 'differences': [150], 'both': [152], 'ET': [165, 197], 'levels': [166], '(156.08±17.39)': [172], 'ng/l,': [173, 175, 182], '(144.91±17.60)': [174], '(150.48±22.94)': [181], '(135.04±10.08)': [183], 'ng/l.': [184], 'Correlation': [185], 'analysis': [186], 'showed': [187], 'that': [188], 'negatively': [192], 'correlated': [193], '(p<0.001).': [198], 'CONCLUSIONS:': [199], 'can': [207], 'improve': [208], 'function': [210], 'capacity': [214], 'disease,': [219], 'reduce': [220], 'production': [222], 'neurotoxic': [224], 'substances': [225], 'ET,': [228], 'provide': [230], 'higher': [231], 'safety.': [232]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3186952914', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 5}, {'year': 2022, 'cited_by_count': 2}], 'updated_date': '2024-12-24T05:43:25.425314', 'created_date': '2021-08-02'}