Title: Relationship between the expression of E-cadherin and MVD and its significance in lung cancer
Abstract: Objective To study the relationship between the expression of E-cadherin and MVD in lung cancer and its significance. Methods The expressions of E-cadherin and factor Ⅷ were detected in 104 lung cancer tissues by immunohistochemical method, and MVD was calculated by image analysis system. Results The expression of E-cadherin was significantly related to the differentiation of lung cancer (P0.05). A negative correlation was observed between E-cadherin expression and MVD in lung cancer tissues (P= 0.047). Conclusion Downexpression of E-cadherin and increase of MVD may play an important role in the invasion and metastasis of lung cancer, and may also be used as a useful marker for tumor prognosis.
Publication Year: 2003
Publication Date: 2003-01-01
Language: en
Type: article
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