Title: Risk factors of metastasis and recurrence for stage II colorectal carcinoma
Abstract: Objective To investigate the risk factors of metastasis and recurrence for stage Ⅱcolorectal carcinoma.Methods From January,2000 to December,2003,clinical records of 192 stage Ⅱ colorectal carcinoma patients who had underwent curative resection were retrospectively analyzed.Results 68 patients experienced relapse,including 19 hepatic metastasis,15 pulmonary metastasis,5 bone metastasis,3 brain metastasis,1 kidney meta stasis and 11 stomal recurrence.Preoperative CEA level,histological differentiation,T stage,lymph node harvest and vessel invasion were the main factors correlated with metastasis/recurrence(χ~2 values were 8.566,7.602,6.505, 11.892 and 6.995,P<O.05).Logistic regression analysis showed that preoperative CEA level,histological differentiation,and lymph node harvested were independent risk factors.Conclusions Liver is the most common metastatic site after curative resection.Improved lymph node harvest could reduce metastasis or recurrence risk.
Key words:
Colorectal neoplasm; Recurrence; Metastasis; Risk factor
Publication Year: 2010
Publication Date: 2010-04-01
Language: en
Type: article
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