Title: CT Manifestation and Pathology in Rabbit with Transplanted Liver Cancer Being Treated with Argon-Helium Cryoablation
Abstract: [Purpose] To investigate the CT and pathologic findings of transplanted liver cancer in rabbit being treated with cryoablation. [Methods] Seventeen rabbits with VX-2 tumors(group A) and 12 healthy rabbits(group B) underwent Argon-Helium cryoablation for tumor and for liver. CT plain scan and enhanced scan were performed before cryoablation, and 1 week, 2 weeks, 3 weeks and 4 weeks after cryoablation. Imaging findings were analyzed and compared with the corresponding histopathology finding. [Results] In the first, second and third week after cryoablation, all cryolesions exhibited low density, no enhancement, accompanied by ring enhancement in margin, with diverse imaging characters. In the fourth week, plain scan showed low density in cryolesions in both groups. Enhancement scan showed the ring enhancement in margin disappeared in group B, but different findings in group A in which some lesions' margins without ring enhancement but others revealed ring enhancement with extension,which pathologicaly demonstrated residual tumor. [Conclusions] Imaging characteristics in 4 weeks after treatment are helpful to evaluate the effect of cryoablation to liver cancer.
Publication Year: 2008
Publication Date: 2008-01-01
Language: en
Type: article
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