Title: Peroxisome Proliferator-activated Receptors (PPARs) and microRNAs
Abstract: The interaction of peroxisome proliferator-activated receptors(PPARs) and microRNAs in cells influences tissue and organ functions. They play important roles in physiological and pathological processes in adipocyte differentiation and metabolism,or in inflammation,cancer and cardiovascular diseases. In this review,the molecular mechanisms of PPARs(PPARα,PPARβ and PPARγ) and their regulated miRNAs,as well as the miRNAs that modulates PPARs expression are summarized. The involved regulatory network and the application prospects are discussed.
Publication Year: 2014
Publication Date: 2014-01-01
Language: en
Type: article
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