Title: The change of kidney ultramicrostructure in diabetes rat
Abstract:Objective To explore the change of Kidney ultramicrostructure in diabetes rat.Methods Set up the model of diabetic rat,at 1、4、8 and 12 weeks,weight、fast Blood glucose were observed.The pathological ch...Objective To explore the change of Kidney ultramicrostructure in diabetes rat.Methods Set up the model of diabetic rat,at 1、4、8 and 12 weeks,weight、fast Blood glucose were observed.The pathological changes of kidney were examined by light microscope and electron microscope.Results Compared with the control group,diabetic rats expressed more 24-hour urinary microalbumin quantitation was significantly higher than the control group(P0.01)at 4 weeks、8 weeks and 12 weeks;The fast blood glucose of diabetic group sustained at high level.Compare with normal control group,the changes of kidney structure was obvious.Conclusion The model of STZ-induced diabetic rats was succeeding.Diabetes mellitus(DM)play important role at mechanism of diabetic nephropathy(DN).Read More
Publication Year: 2008
Publication Date: 2008-01-01
Language: en
Type: article
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