Title: Rheumatoid factor and anti-cyclic citrullinated peptides antibody in diagnosing significance in patients with rheumatoid arthritis and their correlation with disease activity
Abstract:Objective:To evaluate the diagnostic significance through detecting rheumatoid factor(RF-IgM) and anti-cyclic citrullinated peptide(CCP) antibody and their correlation with disease activity.Methods: W...Objective:To evaluate the diagnostic significance through detecting rheumatoid factor(RF-IgM) and anti-cyclic citrullinated peptide(CCP) antibody and their correlation with disease activity.Methods: We used enzyme-linked immunosorbent assay and rate nephelometry to detect CCP and RF in patients with 65 RA,68 non-RA.Results: The sensitivity for RF and anti-CCP were 81.5% and 95.4%,respectively,and the specificity were 58.8%,95.6%,respectively.The specificity was increased by combining the tests.A significant correlation was found between RF,anti-CCP and CRP,ESR,respectively.Conclusion: The higher specificity was achieved by combining the tests.There was an association between RF,anti-CCP and disease activity.Read More
Publication Year: 2011
Publication Date: 2011-01-01
Language: en
Type: article
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