Title: Synthesis of 3-formylindole-7-carboxylic acid
Abstract:3-Formylindole-7-carboxylic acid(1) was synthesized from 3-methyl-2-nitrobenzoic acid as raw material by esterification with MeOH/H_2SO_4,condensation with DMFDMA,reduction with Fe/HOAc and Vilsmeier-...3-Formylindole-7-carboxylic acid(1) was synthesized from 3-methyl-2-nitrobenzoic acid as raw material by esterification with MeOH/H_2SO_4,condensation with DMFDMA,reduction with Fe/HOAc and Vilsmeier-Hacck reaction with POCl_3/DMF in an overall yield of 53%.The structure of 1 was confirmed by(()~1HNMR),IR and MS.Read More
Publication Year: 2006
Publication Date: 2006-01-01
Language: en
Type: article
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