Title: Efficacy Observation of High-dose Omeprazole Treatment in 20 Patients with Severe Pancreatitis
Abstract: Objective To investigate the clinical efficacy of high-dose omeprazole treatment in severe pancreatitis. Methods Forty patients with severe pancreatitis in Affiliated Hospital of Yan' an University were chosen as research subjects. They were randomly divided into study group and control group( n = 20)patients. The study group was given intravenous infusion of high-dose( 80 mg) omeprazole,the control group were treated with conventional doses( 40 mg) of omeprazole,administered for 7-14 days. SPSS 15. 0 statistic software was used to analyze and compare the clinical efficacy and gastrointestinal recovery and hospitalization time of the two groups. Results There were 14 case of markedly effective,5 cases of effective,1 case of ineffective in the study group,the total effective rate was 95%; there were 7 case of markedly effective,5cases of effective,8 case of ineffective in the control group,and the total efficiency was 60%; comparing the two sets of data,the difference was statistically significant( u = 6. 75,P 0. 05); in the study group,the gastrointestinal recovery time was( 6. 9 ± 1. 3) d,hospital stay was( 22. 2 ± 13. 3) d,compared with the control group( 9. 4 ± 1. 5 and 34. 3 ± 14. 2) d,there were statistically significant differences( P 0. 05). Conclusion The use of high-dose omeprazole in patients with severe pancreatitis,can effectively shorten the gastrointestinal tract recovery time and hospital stay of the patients,and improve the cure rate.
Publication Year: 2013
Publication Date: 2013-01-01
Language: en
Type: article
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot