Title: A case control study on the effects and side effects of Lithium and Valproate in treatment of the manic patients
Abstract: Objective: To investigate the therapeutic effects and side effects of Lithium and Valproate in treatment of the manic patients. Methods: Fifty-two patients with mania disorder were divided into two groups. One group was treated with Lithum, another one was treated with sodium Valproate. Bech-Rafaelsen Mania Rating Scale(BRMS) and Treatment Emergent Symptom Scale(TESS) were used to evaluate therapeutic effects and side effects. Results: There is no significant difference between the two groups in therapeutic effects (P0.05). But the side effects in the patients treated with Lithum were much higher than the patients treated with valproate(P0.05). Conclusion: Valproate is better than Lithum in treatment of the patients with mania disorder.
Publication Year: 2006
Publication Date: 2006-01-01
Language: en
Type: article
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