Publication Year: 2012
DOI: https://doi.org/10.1039/c2cs35249d
Abstract: Bioluminescent imaging of applications in bioluminescent imaging. It should be emphasized that these process caged luciferins can stretch out the applications of bioluminescence imaging envisioned and shed light upon understanding the pathogenesis of various diseases. in life sciences. As the most conventional (BLI) technique for BLI, the firefly luciferin–luciferase system Show more
Authors:
Publication Year: 2016
DOI: https://doi.org/10.1038/ncomms11856
Abstract: Abstract In and the near-infrared wavelength ranges (λ max =677 nm), and yields D significantly increased target-detection sensitivity from deep tissues with maximal signals -luciferin attained at very low concentrations, as compared with D -luciferin has and emerging synthetic luciferin CycLuc1. These characteristics offer a more become sensitive and accurate Show more
Authors:
Publication Year: 1963
DOI: https://doi.org/10.1021/ja00886a019
Abstract: ADVERTISEMENT RETURN H. more information about Crossref citation counts.The Altmetric Attention Score is White, a quantitative measure of the attention that a research article Frank. has received online. Clicking on the donut icon will load McCapra, a page at altmetric.com with additional details about the score and and the social Show more
Authors:
Publication Year: 2013
DOI: https://doi.org/10.1021/ja309078t
Abstract: In vivo mechanisms developed Peroxy Caged Luciferin-2 (PCL-2), a H(2)O(2)-responsive boronic acid probe of that releases 6-hydroxy-2-cyanobenzothiazole (HCBT) upon reacting with this reactive oxygen health, species, as well as a peptide-based probe, z-Ile-Glu-ThrAsp-D-Cys (IETDC), which injury, releases D-cysteine in the presence of active caspase 8. Once aging, released, HCBT and Show more
Authors:
Publication Year: 1961
DOI: https://doi.org/10.1021/ja01471a051
Abstract: ADVERTISEMENT RETURN H. updated daily. Find more information about Crossref citation counts.The Altmetric White, Attention Score is a quantitative measure of the attention that Frank a research article has received online. Clicking on the donut McCapra, icon will load a page at altmetric.com with additional details George about the score Show more
Authors:
Publication Year: 2017
DOI: https://doi.org/10.1002/anie.201706969
Abstract: Abstract Bioluminescent imaging tool for imaging in living systems. applications because of their high sensitivity and the simplicity and of the equipment required to perform the measurement. Synthetic luciferin‐analogue chemiluminescent probes with in vivo imaging performance better than that of probes luciferin are now available. In addition, caged luciferin‐based bioluminogenic Show more
Authors:
Publication Year: 2012
DOI: https://doi.org/10.1021/ja301493d
Abstract: Bioluminescence imaging luciferins. Here, we describe a rapid method to synthesize d-luciferin, with the substrate for firefly luciferase (Fluc), along with a novel luciferase set of electronically modified analogues. Our procedure utilizes a relatively enzymes rare, but synthetically useful dithiazolium reagent to generate heteroaromatic scaffolds requires in a divergent fashion. Show more
Authors:
Publication Year: 2017
DOI: https://doi.org/10.1021/jacs.6b11737
Abstract: Bioluminescence imaging research. in vitro and in cultured cell models. Based on their Several selectivity, these designer pairs will bolster multicomponent imaging and enable luciferases the direct interrogation of cell networks not currently possible with have existing tools. Our screening platform is also general and will been expedite the identification Show more
Authors:
Publication Year: 2006
DOI: https://doi.org/10.1021/ja0586283
Abstract: The design, and luciferin are described that release luciferin only after entry synthesis, into cells that are stably transfected with luciferase. Each molecule and of free luciferin that is released after entry generates a evaluation photon that can be measured allowing for real-time quantification of of uptake and release in Show more
Authors:
Publication Year: 2014
DOI: https://doi.org/10.1038/nmeth.2839
Abstract: Not available
Authors:
Publication Year: 1969
DOI: https://doi.org/10.1111/j.1751-1097.1969.tb05676.x
Abstract: Abstract— The and chemiluminescent oxidations of firefly luciferin are elucidated. The colors chemical of firefly bioluminescence can be explained in terms of different steps ionic excited states and spectral shifts due to changes in and molecular environment. Firefly luciferase undergoes conformational changes during catalysis. There the are two sites for Show more
Authors:
Publication Year: 1989
DOI: https://doi.org/10.1021/ja00201a050
Abstract: ADVERTISEMENT RETURN and calculated by Crossref and updated daily. Find more information about nonenzymic Crossref citation counts.The Altmetric Attention Score is a quantitative measure air-oxidation of the attention that a research article has received online. productsHideshi Clicking on the donut icon will load a page at Nakamura, altmetric.com with additional Show more
Authors:
Publication Year: 2016
DOI: https://doi.org/10.1039/c6cs00296j
Abstract: This review and their applications in different fields of science. summarizes the properties of 9 studied bioluminescent systems
Authors:
Publication Year: 1988
DOI: https://doi.org/10.1016/0003-2697(88)90354-5
Abstract: Not available
Authors:
Publication Year: 2004
DOI: https://doi.org/10.1002/bio.749
Abstract: Abstract Bioluminescence, living thiazole carboxylic acid moiety, the former being rarely observed in organisms, nature but the latter being observed in a broad range is of biologically derived molecules. Benzothiazoles are, however, observed in melanogenesis dependent and we speculate as to whether this may be relevant on to the understanding Show more
Authors:
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