Publication Information

{'id': 'https://openalex.org/W2069244797', 'doi': 'https://doi.org/10.1021/ja0586283', 'title': 'Releasable Luciferin−Transporter Conjugates: Tools for the Real-Time Analysis of Cellular Uptake and Release', 'display_name': 'Releasable Luciferin−Transporter Conjugates: Tools for the Real-Time Analysis of Cellular Uptake and Release', 'publication_year': 2006, 'publication_date': '2006-04-25', 'ids': {'openalex': 'https://openalex.org/W2069244797', 'doi': 'https://doi.org/10.1021/ja0586283', 'mag': '2069244797', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/16704230'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1021/ja0586283', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S111155417', 'display_name': 'Journal of the American Chemical Society', 'issn_l': '0002-7863', 'issn': ['0002-7863', '1520-5126', '1943-2984'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320006', 'host_organization_name': 'American Chemical Society', 'host_organization_lineage': ['https://openalex.org/P4310320006'], 'host_organization_lineage_names': ['American Chemical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5110764066', 'display_name': 'Lisa Jones', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I97018004', 'display_name': 'Stanford University', 'ror': 'https://ror.org/00f54p054', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I97018004']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Lisa R. Jones', 'raw_affiliation_strings': ['Departments of Chemistry, Molecular Pharmacology, and Pediatrics, Stanford University, Stanford, California 94305-5080'], 'affiliations': [{'raw_affiliation_string': 'Departments of Chemistry, Molecular Pharmacology, and Pediatrics, Stanford University, Stanford, California 94305-5080', 'institution_ids': ['https://openalex.org/I97018004']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5087614985', 'display_name': 'Elena A. Goun', 'orcid': 'https://orcid.org/0000-0002-4214-0656'}, 'institutions': [{'id': 'https://openalex.org/I97018004', 'display_name': 'Stanford University', 'ror': 'https://ror.org/00f54p054', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I97018004']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Elena A. Goun', 'raw_affiliation_strings': ['Departments of Chemistry, Molecular Pharmacology, and Pediatrics, Stanford University, Stanford, California 94305-5080'], 'affiliations': [{'raw_affiliation_string': 'Departments of Chemistry, Molecular Pharmacology, and Pediatrics, Stanford University, Stanford, California 94305-5080', 'institution_ids': ['https://openalex.org/I97018004']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5072718006', 'display_name': 'Rajesh Shinde', 'orcid': 'https://orcid.org/0000-0001-9478-8676'}, 'institutions': [{'id': 'https://openalex.org/I97018004', 'display_name': 'Stanford University', 'ror': 'https://ror.org/00f54p054', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I97018004']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Rajesh Shinde', 'raw_affiliation_strings': ['Departments of Chemistry, Molecular Pharmacology, and Pediatrics, Stanford University, Stanford, California 94305-5080'], 'affiliations': [{'raw_affiliation_string': 'Departments of Chemistry, Molecular Pharmacology, and Pediatrics, Stanford University, Stanford, California 94305-5080', 'institution_ids': ['https://openalex.org/I97018004']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109090975', 'display_name': 'Jonathan B. Rothbard', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I97018004', 'display_name': 'Stanford University', 'ror': 'https://ror.org/00f54p054', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I97018004']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jonathan B. Rothbard', 'raw_affiliation_strings': ['Departments of Chemistry, Molecular Pharmacology, and Pediatrics, Stanford University, Stanford, California 94305-5080'], 'affiliations': [{'raw_affiliation_string': 'Departments of Chemistry, Molecular Pharmacology, and Pediatrics, Stanford University, Stanford, California 94305-5080', 'institution_ids': ['https://openalex.org/I97018004']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5081671050', 'display_name': 'Christopher H. Contag', 'orcid': 'https://orcid.org/0000-0002-1011-8278'}, 'institutions': [{'id': 'https://openalex.org/I97018004', 'display_name': 'Stanford University', 'ror': 'https://ror.org/00f54p054', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I97018004']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Christopher H. Contag', 'raw_affiliation_strings': ['Departments of Chemistry, Molecular Pharmacology, and Pediatrics, Stanford University, Stanford, California 94305-5080'], 'affiliations': [{'raw_affiliation_string': 'Departments of Chemistry, Molecular Pharmacology, and Pediatrics, Stanford University, Stanford, California 94305-5080', 'institution_ids': ['https://openalex.org/I97018004']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5060002438', 'display_name': 'Paul A. Wender', 'orcid': 'https://orcid.org/0000-0001-6319-2829'}, 'institutions': [{'id': 'https://openalex.org/I97018004', 'display_name': 'Stanford University', 'ror': 'https://ror.org/00f54p054', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I97018004']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Paul A. Wender', 'raw_affiliation_strings': ['Departments of Chemistry, Molecular Pharmacology, and Pediatrics, Stanford University, Stanford, California 94305-5080'], 'affiliations': [{'raw_affiliation_string': 'Departments of Chemistry, Molecular Pharmacology, and Pediatrics, Stanford University, Stanford, California 94305-5080', 'institution_ids': ['https://openalex.org/I97018004']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 3.893, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 142, 'citation_normalized_percentile': {'value': 0.999981, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '128', 'issue': '20', 'first_page': '6526', 'last_page': '6527'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12561', 'display_name': 'bioluminescence and chemiluminescence research', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12561', 'display_name': 'bioluminescence and chemiluminescence research', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10725', 'display_name': 'RNA Interference and Gene Delivery', 'score': 0.9946, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10207', 'display_name': 'Advanced biosensing and bioanalysis techniques', 'score': 0.9931, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/luciferin', 'display_name': 'Luciferin', 'score': 0.90900946}, {'id': 'https://openalex.org/keywords/linker', 'display_name': 'Linker', 'score': 0.5267101}, {'id': 'https://openalex.org/keywords/conjugate', 'display_name': 'Conjugate', 'score': 0.414797}], 'concepts': [{'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.91421217}, {'id': 'https://openalex.org/C2781309008', 'wikidata': 'https://www.wikidata.org/wiki/Q369745', 'display_name': 'Luciferin', 'level': 5, 'score': 0.90900946}, {'id': 'https://openalex.org/C149011108', 'wikidata': 'https://www.wikidata.org/wiki/Q652985', 'display_name': 'Transporter', 'level': 3, 'score': 0.63891864}, {'id': 'https://openalex.org/C111335760', 'wikidata': 'https://www.wikidata.org/wiki/Q95385166', 'display_name': 'Luciferase', 'level': 4, 'score': 0.5406631}, {'id': 'https://openalex.org/C2780557392', 'wikidata': 'https://www.wikidata.org/wiki/Q523796', 'display_name': 'Linker', 'level': 2, 'score': 0.5267101}, {'id': 'https://openalex.org/C12554922', 'wikidata': 'https://www.wikidata.org/wiki/Q7100', 'display_name': 'Biophysics', 'level': 1, 'score': 0.52095354}, {'id': 'https://openalex.org/C197336794', 'wikidata': 'https://www.wikidata.org/wiki/Q5161150', 'display_name': 'Conjugate', 'level': 2, 'score': 0.414797}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.40695313}, {'id': 'https://openalex.org/C54009773', 'wikidata': 'https://www.wikidata.org/wiki/Q1429031', 'display_name': 'Transfection', 'level': 3, 'score': 0.33772424}, {'id': 'https://openalex.org/C134306372', 'wikidata': 'https://www.wikidata.org/wiki/Q7754', 'display_name': 'Mathematical analysis', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C33923547', 'wikidata': 'https://www.wikidata.org/wiki/Q395', 'display_name': 'Mathematics', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C111919701', 'wikidata': 'https://www.wikidata.org/wiki/Q9135', 'display_name': 'Operating system', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D001692', 'descriptor_name': 'Biological Transport', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D049454', 'descriptor_name': 'Firefly Luciferin', 'qualifier_ui': 'Q000031', 'qualifier_name': 'analogs & derivatives', 'is_major_topic': True}, {'descriptor_ui': 'D015082', 'descriptor_name': "2,2'-Dipyridyl", 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015082', 'descriptor_name': "2,2'-Dipyridyl", 'qualifier_ui': 'Q000031', 'qualifier_name': 'analogs & derivatives', 'is_major_topic': False}, {'descriptor_ui': 'D015082', 'descriptor_name': "2,2'-Dipyridyl", 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001692', 'descriptor_name': 'Biological Transport', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002477', 'descriptor_name': 'Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002477', 'descriptor_name': 'Cells', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D004220', 'descriptor_name': 'Disulfides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004220', 'descriptor_name': 'Disulfides', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D004220', 'descriptor_name': 'Disulfides', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D049454', 'descriptor_name': 'Firefly Luciferin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008156', 'descriptor_name': 'Luciferases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008156', 'descriptor_name': 'Luciferases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008163', 'descriptor_name': 'Luminescent Measurements', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011471', 'descriptor_name': 'Prostatic Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011471', 'descriptor_name': 'Prostatic Neoplasms', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D014162', 'descriptor_name': 'Transfection', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1021/ja0586283', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S111155417', 'display_name': 'Journal of the American Chemical Society', 'issn_l': '0002-7863', 'issn': ['0002-7863', '1520-5126', '1943-2984'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320006', 'host_organization_name': 'American Chemical Society', 'host_organization_lineage': ['https://openalex.org/P4310320006'], 'host_organization_lineage_names': ['American Chemical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/16704230', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 12, 'referenced_works': ['https://openalex.org/W1479813612', 'https://openalex.org/W1585317376', 'https://openalex.org/W1590085201', 'https://openalex.org/W164491649', 'https://openalex.org/W1963819255', 'https://openalex.org/W1980873645', 'https://openalex.org/W2024128913', 'https://openalex.org/W2033191256', 'https://openalex.org/W2086523446', 'https://openalex.org/W2094532912', 'https://openalex.org/W2103149664', 'https://openalex.org/W4241539519'], 'related_works': ['https://openalex.org/W4301514381', 'https://openalex.org/W2317157107', 'https://openalex.org/W2164217665', 'https://openalex.org/W2141560453', 'https://openalex.org/W2072914526', 'https://openalex.org/W2037413647', 'https://openalex.org/W2032336836', 'https://openalex.org/W1981359126', 'https://openalex.org/W1930500389', 'https://openalex.org/W1541569832'], 'abstract_inverted_index': {'The': [0, 55], 'design,': [1], 'synthesis,': [2], 'and': [3, 10, 51, 63, 77], 'evaluation': [4], 'of': [5, 7, 30, 49, 65, 71], 'conjugates': [6], 'arginine-rich': [8], 'transporters': [9], 'luciferin': [11, 16, 32, 67], 'are': [12, 23], 'described': [13], 'that': [14, 22, 33, 41], 'release': [15, 52, 64], 'only': [17], 'after': [18, 36], 'entry': [19, 37], 'into': [20], 'cells': [21], 'stably': [24], 'transfected': [25], 'with': [26], 'luciferase.': [27], 'Each': [28], 'molecule': [29], 'free': [31, 66], 'is': [34], 'released': [35], 'generates': [38], 'a': [39, 58, 69], 'photon': [40], 'can': [42], 'be': [43], 'measured': [44], 'allowing': [45], 'for': [46], 'real-time': [47], 'quantification': [48], 'uptake': [50, 62], 'in': [53, 73, 78], 'cells.': [54], 'process': [56], 'provides': [57], 'method': [59], 'to': [60], 'assay': [61], 'as': [68], 'function': [70], 'variations': [72], 'the': [74, 79], 'releasable': [75], 'linker': [76], 'transporter.': [80]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2069244797', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 8}, {'year': 2020, 'cited_by_count': 8}, {'year': 2019, 'cited_by_count': 9}, {'year': 2018, 'cited_by_count': 9}, {'year': 2017, 'cited_by_count': 11}, {'year': 2016, 'cited_by_count': 11}, {'year': 2015, 'cited_by_count': 12}, {'year': 2014, 'cited_by_count': 5}, {'year': 2013, 'cited_by_count': 11}, {'year': 2012, 'cited_by_count': 7}], 'updated_date': '2025-01-06T22:11:01.694500', 'created_date': '2016-06-24'}