Publication Information

{'id': 'https://openalex.org/W3031664073', 'doi': 'https://doi.org/10.3760/cma.j.issn.2095-0160.2008.03.012', 'title': 'Expression of matrix metalloproteinase 9 protein during the developing of human retina', 'display_name': 'Expression of matrix metalloproteinase 9 protein during the developing of human retina', 'publication_year': 2008, 'publication_date': '2008-03-15', 'ids': {'openalex': 'https://openalex.org/W3031664073', 'doi': 'https://doi.org/10.3760/cma.j.issn.2095-0160.2008.03.012', 'mag': '3031664073'}, 'language': 'zh-cn', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://jglobal.jst.go.jp/en/detail?JGLOBAL_ID=201702242254068644', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764489546', 'display_name': 'Zhonghua shiyan yanke zazhi', 'issn_l': '2095-0160', 'issn': ['2095-0160'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4320800525', 'host_organization_name': 'Chinese Medical Association', 'host_organization_lineage': ['https://openalex.org/P4320800525'], 'host_organization_lineage_names': ['Chinese Medical Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': [], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5040839623', 'display_name': 'Huiming Li', 'orcid': 'https://orcid.org/0009-0002-7891-5932'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Li Huiming', 'raw_affiliation_strings': ['200080,上海交通大学附属第一人民医院中心实验室'], 'affiliations': [{'raw_affiliation_string': '200080,上海交通大学附属第一人民医院中心实验室', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101672779', 'display_name': 'Wei Qiu', 'orcid': 'https://orcid.org/0000-0003-1562-9197'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Qiu Wei', 'raw_affiliation_strings': ['200080,上海交通大学附属第一人民医院中心实验室'], 'affiliations': [{'raw_affiliation_string': '200080,上海交通大学附属第一人民医院中心实验室', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5045389093', 'display_name': 'Feng Wang', 'orcid': 'https://orcid.org/0000-0002-4322-2127'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Wang Feng', 'raw_affiliation_strings': ['200080,上海交通大学附属第一人民医院中心实验室'], 'affiliations': [{'raw_affiliation_string': '200080,上海交通大学附属第一人民医院中心实验室', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5000362409', 'display_name': 'Ma Jialie', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Ma Jialie', 'raw_affiliation_strings': ['200080,上海交通大学附属第一人民医院中心实验室'], 'affiliations': [{'raw_affiliation_string': '200080,上海交通大学附属第一人民医院中心实验室', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5034055532', 'display_name': 'Yi Miaoying', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Yi Miaoying', 'raw_affiliation_strings': ['200080,上海交通大学附属第一人民医院中心实验室'], 'affiliations': [{'raw_affiliation_string': '200080,上海交通大学附属第一人民医院中心实验室', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5045787470', 'display_name': 'Yufei Wang', 'orcid': 'https://orcid.org/0000-0003-3713-6174'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Wang Yufei', 'raw_affiliation_strings': ['200080,上海交通大学附属第一人民医院糖尿病研究室'], 'affiliations': [{'raw_affiliation_string': '200080,上海交通大学附属第一人民医院糖尿病研究室', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5060120779', 'display_name': 'Qian Huang', 'orcid': 'https://orcid.org/0000-0002-4474-3848'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Huang Qian', 'raw_affiliation_strings': ['200080,上海交通大学附属第一人民医院中心实验室'], 'affiliations': [{'raw_affiliation_string': '200080,上海交通大学附属第一人民医院中心实验室', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 63}, 'biblio': {'volume': '26', 'issue': '03', 'first_page': '208', 'last_page': '210'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10620', 'display_name': 'Protease and Inhibitor Mechanisms', 'score': 0.9631, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10620', 'display_name': 'Protease and Inhibitor Mechanisms', 'score': 0.9631, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11480', 'display_name': 'Connexins and lens biology', 'score': 0.9576, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10170', 'display_name': 'Retinal Diseases and Treatments', 'score': 0.9523, 'subfield': {'id': 'https://openalex.org/subfields/2731', 'display_name': 'Ophthalmology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/matrix-metalloproteinase-9', 'display_name': 'Matrix metalloproteinase 9', 'score': 0.52852887}, {'id': 'https://openalex.org/keywords/matrix', 'display_name': 'Matrix (chemical analysis)', 'score': 0.4307639}], 'concepts': [{'id': 'https://openalex.org/C109523444', 'wikidata': 'https://www.wikidata.org/wiki/Q424216', 'display_name': 'Matrix metalloproteinase', 'level': 2, 'score': 0.6861526}, {'id': 'https://openalex.org/C2777093970', 'wikidata': 'https://www.wikidata.org/wiki/Q169342', 'display_name': 'Retina', 'level': 2, 'score': 0.6076668}, {'id': 'https://openalex.org/C2991819120', 'wikidata': 'https://www.wikidata.org/wiki/Q13033749', 'display_name': 'Matrix metalloproteinase 9', 'level': 3, 'score': 0.52852887}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.51124716}, {'id': 'https://openalex.org/C55728118', 'wikidata': 'https://www.wikidata.org/wiki/Q425402', 'display_name': 'Metalloproteinase', 'level': 3, 'score': 0.4641764}, {'id': 'https://openalex.org/C106487976', 'wikidata': 'https://www.wikidata.org/wiki/Q685816', 'display_name': 'Matrix (chemical analysis)', 'level': 2, 'score': 0.4307639}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.34056765}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.25548658}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.17367557}, {'id': 'https://openalex.org/C43617362', 'wikidata': 'https://www.wikidata.org/wiki/Q170050', 'display_name': 'Chromatography', 'level': 1, 'score': 0.09037724}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.06634697}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://jglobal.jst.go.jp/en/detail?JGLOBAL_ID=201702242254068644', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764489546', 'display_name': 'Zhonghua shiyan yanke zazhi', 'issn_l': '2095-0160', 'issn': ['2095-0160'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4320800525', 'host_organization_name': 'Chinese Medical Association', 'host_organization_lineage': ['https://openalex.org/P4320800525'], 'host_organization_lineage_names': ['Chinese Medical Association'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W378299785', 'https://openalex.org/W3032736425', 'https://openalex.org/W3032119383', 'https://openalex.org/W3031769697', 'https://openalex.org/W3031624437', 'https://openalex.org/W3031534618', 'https://openalex.org/W3030953775', 'https://openalex.org/W3030692868', 'https://openalex.org/W3030112887', 'https://openalex.org/W3030015305', 'https://openalex.org/W3029779073', 'https://openalex.org/W3029697296', 'https://openalex.org/W3029642147', 'https://openalex.org/W3029095879', 'https://openalex.org/W2679010736', 'https://openalex.org/W2523328452', 'https://openalex.org/W2389601191', 'https://openalex.org/W2087285445', 'https://openalex.org/W2036945347', 'https://openalex.org/W1973318102'], 'abstract_inverted_index': {'目的': [0], '观察人视网膜发育和分化过程中基质金属蛋白酶9(MMP-9)的表达水平与细胞分布特点,探讨其在人视网膜发育和分化过程中的可能作用.方法': [1], '胚胎发育早期、中晚期及成人视网膜石蜡切片,抗MMP-9免疫组织化学染色,观察MMP-9表达水平和分布的变化.结果': [2], '胚胎发育早期的视网膜仅在外成神经细胞层的外侧可见弱阳性细胞;胚胎发育中期外成神经细胞层的外侧,即将来要发育成盘膜处出现明显的特异性染色,而其他细胞染色仍然较弱;成人视网膜的外核层出现显著的特异性染色细胞,胞质明显着色,胞体轮廓清晰,并可观察到锥体的结构以及突触的特异染色,判断这些细胞主要是光感受器细胞中的视锥细胞.结论': [3], 'MMP-9在视网膜中的表达与视网膜的成熟和细胞分化关系密切,在光感受器中的视锥细胞高水平表达,提示MMP-9可能参与视觉信号的处理。': [4]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3031664073', 'counts_by_year': [], 'updated_date': '2024-12-14T07:20:14.984164', 'created_date': '2020-06-05'}