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'探讨基质金属蛋白酶(matrix': [1], 'metalloproteinases,MMP)与人脑星形胶质细胞瘤浸润性生长之间的关系,以及基质金属蛋白酶的阳性表达与星形胶质细胞瘤病理分级的关系.方法应用免疫组织化学染色法(SP法)检测44例人脑星形胶质细胞瘤组织中MMp-2、MMP-9的表达.结果Ⅲ、Ⅳ级中MMP-2、MMP-9蛋白的表达显著高于Ⅰ、Ⅱ级,而正常脑组织中无表达;在人脑星形胶质细胞瘤中MMP-2和MMP-9的表达之间无明显相关性.结论MMP-2、MMP-9的表达与星形胶质细胞瘤的恶性程度有关,其高表达可能与星形胶质细胞瘤的侵袭转移有关。': [2]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W3031624437', 'counts_by_year': [], 'updated_date': '2024-12-15T16:49:43.676205', 'created_date': '2020-06-05'}