Title: Experimental Study of the Tonifying Kidney and Promoting Blood Circulation Prescription's Inhibition of Hyperirritable Oxidation of the Diabetic Rat's Kidney and Pancreas Tissue
Abstract: Objective:To analyse the tonifying kidney and promoting blood circulation prescription's inhibition of hyperirritable oxidation of the diabetic rat's kidney and pancreas tissue.Methods:The SD rats are divided into 4 groups:natural comparison group(A group),small dose group(B group),great dose group(C group),DM group(D group).B,C,D groups are formed DM model and administered the tonifying kidney and promoting blood circulation prescription(B group:18g/kg;C group:26g/kg).After 6 weeks,executing the rats by breaking their necks and getting their left kidneys and pancreata immediately to be formed into 10% thick fluid with physiological saline.Mensurating concentration of MDA、GSH-Px and SOD in kidney and pancreas tissue.Results The diabetic rat's concentration of MDA increases evidently and their concentration of GSH-Px,SOD decreases evidently.The tonifying kidney and promoting blood circulation prescription can increase concentration of GSH-Px and SOD in kidney tissue and GSH-Px in pancreas tissue.Conclusion:The prescription has antioxidation to protect the kidney function through increasing concentration of GSH-Px and SOD in kidney tissue and GSH-Px in pancreas tissue.
Publication Year: 2007
Publication Date: 2007-01-01
Language: en
Type: article
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