Title: Effects of tonifying kidney,strengthening spleen and tonifying spleen-kidney on peripheral blood T cells in chronic hepatitis patients
Abstract: Objective To compare the effects of of tonifying kidney,strengthening spleen and tonifying spleen-kidney on peripheral blood T cells in chronic hepatitis patients.Methods The peripheral blood anticoagulant from 24 patients with chronic hepatitis and 10 healthy people were separated for peripheral blood mononuclear cells(PBMCs),further,T cells were extracted,separted and cultured,then,the T cells were interfered by plasma with the three groups of Chinese medicines.The expression of CD3+,CD4+,CD8+ and CD28+ in T cells were detected.Results After intervened by the medicated plasma including three groups of medicines,the levels of CD4+ expression were higher(P0.05),the levels of CD8+ expression were lower(P0.05);after intervened by medicated plasma including tonifying kidney medicines,the level of CD3+ expression were higher;after intervened by medicated plasma including tonifying kidney and tonifying spleen-kidney medicines,the levels of CD28+ expression were higher(P0.05).Conclusion All the three groups of medicines can regulate T cells in patients,and the tonifying kidney method is more signicant.
Publication Year: 2011
Publication Date: 2011-01-01
Language: en
Type: article
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