Title: Clinical application of serum Cyst- C and urinary microalbumin in early kidney damage in asphyxiated neonates
Abstract: Objective To investigate the clinical significance of serum Cyst- C and urinary microalbumin in early renal impairment in asphyxiated neonates. Methods Sixty newborn infant with asphyxia in our hospital from January2012 to December 2013 were enrolled in this study. Thirty healthy full term newborn infant were used as the controls. Contents of serum Cyst- C and urinary microalbum were measured respectively. Urinary routine examination was performed in study group. Results The contents of serum Cyst- C( 2. 24 ± 0. 81 mg /L) and urinary microalbumin( 20. 04 ± 10. 32 mg /L) in study group were significantly higher than those in the control( 0. 85 ± 0. 20 mg /L and2. 30 ± 1. 38mg /L respectively; P 0. 01). The proportion of urinary routine abnormality( 35. 0%) was significantly lower than that of urinary microalbumin( 61. 7%) and serum Cyst- C abnormalities( 71. 7%) in study group( P 0. 01). Conclusions Serum Cyst- C and urinary microalbumin may serve as indexes in the assessment of early renal impairment in asphyxiated neonates.
Publication Year: 2014
Publication Date: 2014-01-01
Language: en
Type: article
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