Title: Application of NAG and mALB in diagnose of early renal disease
Abstract: Objective: To provide diagnostic basis for early renal disease,Measuring both urinary NAG and urinary microalbumin can get a higher positive rate.Methods: Urinary N-acetyl-β-D-glucosaminidade (NAG)and blood urea were determined with rate,Urinary creatinine was determined with Jaffe's rate,mALB levels was measured with rate nepherometry. Results: The levels of urinary NAG and blood urea in the controls were (9.37±4.21)IU/gCr and (4.71±1.50)mmol/L,urinary mALB was (12±10)μg/ml. The level of urinary NAG and urinary microalbumin in each group (diabetes,hypertension,lupus erythematosus and uretha infection)were obviously higher than that in the control( P 0.001); Blood urea in diabetes and hypertension groups were higher than that in the control ( P 0.001, P 0.05),In lupus erythematosus and urethra infection weren't higher.Positive rates of urinary NAG in diabetes,hypertension,lupus erythematosus and urethra infection groups were 56.25%,52.17% ,40% and 40%,respectively.They were higher than the positive rate of blood urea by 34.37%,34.78%,20.% and 26.67%,respectively. Positive rates of urinary microalbumin in diabetes,hypertension,lupus erythematosus and urethra infection groups were 50%,47.82% ,50% and 46.67%,respectively.They were higher than the positive rate of blood urea by 28.12%,30.43%,30.% and 33.34%,respectively. Conclusion: The urinary NAG and urinary mALB is sensitive and reliable for diagnose of early renal disease.
Publication Year: 2002
Publication Date: 2002-01-01
Language: en
Type: article
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