Title: Shugan Huoxue Decoction Combined with Adefovir Dipivoxil in the Treatment of HBeAg Positive Chronic Hepatitis B patients Randomized Controlled Study
Abstract: [Objective] To observe the Shugan Huoxue recipe combined with adefovir dipivoxil in the treatment of HBeAg positive chronic hepatitis B patients. [Methods] Using randomized controlled methods, 92 cases of hospitalized patients were randomly divided into two groups numbering method. A control group of46 cases of adefovir dipivoxil, 10mg/, 1 /d, oral. The treatment group of 46 cases of Shugan Huoxue Recipe(Yinchen, Yujin each 4g, Zelan 8g, Baizhu 6g, Baishao 10g, Fuling, Jike each 8g, Chaihu 20g, Jinqiancao 8g, Chishao 4g), 1 doses of /d, water simmer in water 200mL, sooner or later oral. Adefovir dipivoxil treatment with the control group. Continuous treatment with 30d for 1 courses. Observation of clinical symptoms, the time index, CLDQ score, adverse reaction. 1 courses of treatment, the curative effect. [Results] The treatment group cured 18 cases, effective 24 cases, invalid 4 cases, the total efficiency of 91.30%. The control group cured 14 cases, effective 19 cases, invalid 13 cases, the total efficiency of 71.74%. The treatment group was better than control group(P 0.05). The time index(index of liver function recovery time, the results of HBeAg clinical drug treatment program complete clearance time, implementation of the total time) treatment group was less than that of the control group(P 0.05). The CLDQ score of two groups were improved, the treatment group was better than the control group(P 0.05). [Conclusion] Shugan Huoxue Decoction Combined with adefovir dipivoxil in the treatment of HBeAg positive chronic hepatitis B effect is significant, worthy of promotion.
Publication Year: 2014
Publication Date: 2014-01-01
Language: en
Type: article
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