Title: Analysis of Short-Term Therapeutic Effect of Omeprazole and Rabeprazole on Refractory Digestive Ulcer under Gastroscope
Abstract: Objective To analyze and compare the short-term therapeutic efficacy of omeprazole and rabeprazole on refractory digestive ulcer. Methods 78 patients with refractory ulcer during 2008 to 2011 in our hospital were randomly divided into control group and experimental group with 39 cases in each group. The control group was treated with omeprazole trigeminy therapy, while the experimental group was treated with rapeprazole therapy. Gatroscope was operated after treatment to evaluate and compare the short-term effectiveness. Results The experiment group had a significantly higher effective rate of 87.13% than the control group of 53.87% (P 0.05). The clearance of Helicobacter pylori (Hp) of control group was 94.87% and the experiment group was 97.43%. The two groups had no significant difference (P 0.05). None of the two groups was reported to have serious complications. Conclusions Rabeprazole-based triple therapy can effectively inhibit gastric acid secretion, clear Helicobacter pylori, and promote ulcer healing, which has preferable short-term therapeutic efficacy for refractory digestive ulcer.
Publication Year: 2012
Publication Date: 2012-01-01
Language: en
Type: article
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