Publication Information

{'id': 'https://openalex.org/W2381151173', 'doi': None, 'title': 'Inhibitory effect of a novel 2-aminosteroid on the proliferation of K562 leukemia cells', 'display_name': 'Inhibitory effect of a novel 2-aminosteroid on the proliferation of K562 leukemia cells', 'publication_year': 2002, 'publication_date': '2002-01-01', 'ids': {'openalex': 'https://openalex.org/W2381151173', 'mag': '2381151173'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://en.cnki.com.cn/Article_en/CJFDTOTAL-HNYD200205003.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2755450086', 'display_name': "Hu'nan Yike Daxue xuebao", 'issn_l': '1000-5625', 'issn': ['1000-5625'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4361181842', 'host_organization_name': 'Hunan Medical University', 'host_organization_lineage': ['https://openalex.org/P4361181842'], 'host_organization_lineage_names': ['Hunan Medical University'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': [], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5007351226', 'display_name': 'Qun He', 'orcid': 'https://orcid.org/0000-0002-3366-7501'}, 'institutions': [], 'countries': [], 'is_corresponding': True, 'raw_author_name': 'HE Qun', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': ['https://openalex.org/A5007351226'], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.0, 'has_fulltext': False, 'cited_by_count': 0, 'citation_normalized_percentile': {'value': 0.0, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 0, 'max': 57}, 'biblio': {'volume': None, 'issue': None, 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10911', 'display_name': 'Chemical Synthesis and Analysis', 'score': 0.9633, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10911', 'display_name': 'Chemical Synthesis and Analysis', 'score': 0.9633, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11845', 'display_name': 'Cancer therapeutics and mechanisms', 'score': 0.9047, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/k562-cells', 'display_name': 'K562 cells', 'score': 0.91256356}, {'id': 'https://openalex.org/keywords/mtt-assay', 'display_name': 'MTT assay', 'score': 0.74864495}], 'concepts': [{'id': 'https://openalex.org/C171122931', 'wikidata': 'https://www.wikidata.org/wiki/Q6324626', 'display_name': 'K562 cells', 'level': 3, 'score': 0.91256356}, {'id': 'https://openalex.org/C2780783641', 'wikidata': 'https://www.wikidata.org/wiki/Q738686', 'display_name': 'MTT assay', 'level': 3, 'score': 0.74864495}, {'id': 'https://openalex.org/C2778461978', 'wikidata': 'https://www.wikidata.org/wiki/Q29496', 'display_name': 'Leukemia', 'level': 2, 'score': 0.653293}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.5936387}, {'id': 'https://openalex.org/C62112901', 'wikidata': 'https://www.wikidata.org/wiki/Q189159', 'display_name': 'Cell growth', 'level': 2, 'score': 0.5511323}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.5102415}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.48867467}, {'id': 'https://openalex.org/C81885089', 'wikidata': 'https://www.wikidata.org/wiki/Q189082', 'display_name': 'Cell culture', 'level': 2, 'score': 0.4576572}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.3715387}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.260661}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.2586565}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.17023948}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.0}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://en.cnki.com.cn/Article_en/CJFDTOTAL-HNYD200205003.htm', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2755450086', 'display_name': "Hu'nan Yike Daxue xuebao", 'issn_l': '1000-5625', 'issn': ['1000-5625'], 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/P4361181842', 'host_organization_name': 'Hunan Medical University', 'host_organization_lineage': ['https://openalex.org/P4361181842'], 'host_organization_lineage_names': ['Hunan Medical University'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3206645031', 'https://openalex.org/W3150278634', 'https://openalex.org/W3096737239', 'https://openalex.org/W3032270410', 'https://openalex.org/W3031525308', 'https://openalex.org/W3030618826', 'https://openalex.org/W2394298293', 'https://openalex.org/W2392482761', 'https://openalex.org/W2391151595', 'https://openalex.org/W2386320185', 'https://openalex.org/W2384960403', 'https://openalex.org/W2383227951', 'https://openalex.org/W2367840420', 'https://openalex.org/W2366424533', 'https://openalex.org/W2357254117', 'https://openalex.org/W2354832715', 'https://openalex.org/W2187307458', 'https://openalex.org/W2031058777', 'https://openalex.org/W1953625789', 'https://openalex.org/W157523459'], 'abstract_inverted_index': {'Objective': [0], 'To': [1], 'evaluate': [2], 'the': [3, 13, 25, 56, 64, 73, 83, 92, 104, 126, 139], 'inhibitory': [4], 'effects': [5, 21], 'of': [6, 15, 22, 27, 37, 66, 100, 156], 'a': [7, 172], 'novel': [8], '2': [9], 'aminosteroid': [10], '(MPZ)': [11], 'on': [12, 24, 107], 'proliferation': [14, 26, 155], 'K562': [16, 28, 67, 101, 129, 157], 'leukemia': [17, 29, 68, 158], 'cells.': [18], 'Methods': [19], 'The': [20, 98, 154], 'MPZ': [23, 78, 88, 149, 163], 'cells': [30, 69, 102, 130, 159], 'were': [31, 131], 'in': [32, 35, 44, 47, 55, 91, 103, 171], 'vitro': [33], 'studied': [34], 'terms': [36], 'morphology': [38], 'observation,': [39], 'cell': [40], 'number': [41], 'numeration': [42], 'both': [43], 'liquid': [45, 93], 'and': [46, 52, 80, 112, 119, 135, 144], 'semi': [48], 'solid': [49], 'colony': [50, 105], 'cultures': [51], 'UV': [53], 'absorption': [54], 'MTT': [57, 127], 'assay.': [58], 'Results': [59], 'It': [60], 'was': [61, 70, 110, 160], 'verified': [62], 'that': [63], 'inhibition': [65, 99], '46%': [71], 'with': [72, 82, 141], '10': [74, 84, 117, 120, 142, 145], '-8': [75, 118, 143, 165], 'mol·L': [76, 86, 122, 147, 168], '-1': [77, 87, 123, 148, 169], 'treatment': [79, 89, 140], '83%': [81], '-5': [85, 121, 146, 167], 'respectively': [90, 115, 137], 'culture': [94], 'for': [95, 150], '6': [96], 'days.': [97, 152], 'assay': [106], 'day': [108], '8': [109], '52%': [111], '100%': [113], 'implemented': [114], 'by': [116, 133, 162], 'MPZ.': [124], 'In': [125], 'assay,': [128], 'inhibited': [132, 161], '29%': [134], '88%': [136], 'after': [138], '5': [151], 'Conclusion': [153], '(10': [164], '～10': [166], ')': [170], 'dose': [173], 'dependent': [174], 'manner.': [175]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2381151173', 'counts_by_year': [], 'updated_date': '2024-12-11T23:02:08.998643', 'created_date': '2016-06-24'}