Title: Effects of electric acupuncture on the oxidative stress in the rat of Parkinson’s disease abductioned by rotenone
Abstract: Objective: To observe the effects of electric acupuncture on the oxidative stress in the rat of Parkinson’s disease abductioned by rotenone.Methods: All rats were randomly divided into blank group,model group,electroacupuncture pretreatment group,electroacupuncture treat for one week group,electroacupuncture treat for two weeks group,electroacupuncture treat for three weeks group,electroacupuncture treat for four weeks group.The Parkinson disease model was established by subcutaneous injection of rotenone.The contents of SOD,GSH,CAT,MDA were detected by ultraviolet spectrophotometry.And the expressions of tyrosine hydroxylase(TH) in substantia nigra were detected by immunohistochemistry.Result: Compared with the model group,the electroacupuncture pretreatment group and acupuncture group had the higher contents of SOD,GSH,CAT,and lower content of MDA.The TH positive dopamine neurons in substantia nigra was increased.Conclusion: The acupuncture can obviously increase the rat’s resistance of oxidative stress.
Publication Year: 2013
Publication Date: 2013-01-01
Language: en
Type: article
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Cited By Count: 1
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