Title: Expression of P-selection in colorectal carcinoma tissue
Abstract: Aim: To explore the relationship between the expression of P-selection and invasion and matastasis in colorectal carcinoma tissue.Methods: The expression of P GAAB2 selectin in 8 cases of normal colorectal tissue,47 cases of colorectal carcinoma tissue,and the adjacent tissue was detected using immunohistochemistry. Results: The expression of P-selectin in normal tissue and para-carcinoma tissue was negative. The positive expression rate in colorectal carcinoma tissue was 59.6% (28/47),significantly higher than those in para-carcinoma and normal tissue (P0.05).The expression of P-selectin in carcinoma tissue was not correlated with age,sex,morphology, or differentiation(P0.05),but with lymph node metastasis.Conclusion: The expression of P-selection is associated with metastasis of colorectal carcinoma.
Publication Year: 2005
Publication Date: 2005-01-01
Language: en
Type: article
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