Title: Effect observation of telmisartan combined with nifedipine in the treatment of hypertension
Abstract: Objective To investigate the effect telmisartan combined with nifedipine in the treatment of moderate and severe primary hypertension patients. Methods The clinical data of 200 cases of severe hypertensive patients in our hospital from April 2008 to December 2011 was retrospectively analyzed,the control group(100 cases) was treated with nifedipine,the treatment group(100 cases) was treated with nifedipine extended release tablets combined with telmisartan. The curative effect of the two groups was analyzed by casual and dynamic blood pressure monitoring. Results The effective rate of the treatment group was 95%.which was significantly higher than that of the control group(83%)( χ2=3.972,P0.05);in the aspect of 24 h mean blood pressure,daytime mean blood pressure and nighttime blood pressure mean,the differences of the two groups before and after treatment were significantly significant( P0.05),but the comparison between the two groups with no significant differences(P0.05);there were all significant difference of the blood pressure rhythm in the two groups before and after the treatment(P0.05),the comparison between the two groups was significant differences(P0.05). Conclusion Nifedipine extended release tablets combined with telmisartan oral can effectively control the 24 h blood pressure,with safe,reliable and good tolerance,and less adverse reaction.
Publication Year: 2013
Publication Date: 2013-01-01
Language: en
Type: article
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