Title: The animal model of oculomotor nerves injury for electrophysiological research
Abstract: Objective To establish a feasible and reproducible dog model of oculomotor nerves injury, and to investigate the physiological electric for ocuolomotor nerves regeneration and recovery. Methods Experiment was carried out on 20 normal adult Beagle dogs. All Beagle dogs were distributed equally simplex crush injury and crush plus electrical stimulation groups randomly. Ophthalmic and intracranial operations in Beagle dogs comprised electrode implantation of the right inferior obliquns and simplex crush injury or crush plus electrode implantation of the right oculomotor nerve behind of cavernous sinus. Results All the procedures used in the study were well tolerated by Beagle canines. Electrode implantation of the right inferior obliquus and the right oculomotor nerve behind of cavernous sinus was successful. The compound muscle action potentials (CMAPs) and muscle units potentials (MUPs)were recorded successfully. Conclusion The animal models have been established to study the physiological electric for ocuolomotor nerves regeneration and recovery and have shown great reproductibility and feasibility.
Key words:
Ocuolomotor nerve; Electrophysiology; Models, animal; Dogs
Publication Year: 2006
Publication Date: 2006-01-01
Language: en
Type: article
Access and Citation
Cited By Count: 1
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot