Title: Establishment of An Animal Model of Oculomotor Nerve Injury
Abstract: Objective To create a more feasible and reproducible dog model for oculomotor nerves injury study.Methods The posterior segments of oculomotor nerves in cavernous sinus were exposed in 10 Beagle canines after craniotomy.Various neurophysiologic parameters were recorded,and the compound muscle action potentials(CMAPs)of obliquus inferior muscle were also recorded successfully.After cutting the oculomotor nerves, end-to-end anatomosis was performed to make anatomical reconstruction of the damaged oculomotor nerves immediately.Results All the procedures used in the study had been well tolerated by Beagle canines.Ocolomotor nerves were exposed completely, end-to-end anatomosis were done successfully.Conclusion This larger animal model established helps to study the functional reconstruction of oculomotor nerves after injury and shows great reproducibility.
Publication Year: 2005
Publication Date: 2005-01-01
Language: en
Type: article
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Cited By Count: 2
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