Title: A study of morphological change of ischemia reperfusion and cell apoptosis in rat brain
Abstract: Objective To study the relationship between morphological changes of ischemia reperfusion and cell apoptosis in rat brain and to prove theoretic basis for treating cerebral ischemia. Methods A model with ischemia-reperfusion was established in rat brain by HE,TTC,Thionine and TUNEL dyeing.Results There was no morphology change and clinical meaning in sham operated group. Similar pathological change in permanent occluded and reperfussed group was found 48h after operation.Pathological repair was more remarkable in the reperfused than the occluded group 8 days after operation.The number of apoptosis cell was decreased on boundary in reperfused .Conclusion Reperfusion after ischemia is advantageous to the recovery of the cerebral ischemia in the later stage,but at the same time it may lead to slight damage of nervous cells.
Publication Year: 2002
Publication Date: 2002-01-01
Language: en
Type: article
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot